HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：RAW264.7

External ID: CHEMBL3379705

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 2
First Page: 266
Last Page: 269
DOI: 10.1016/j.bmcl.2014.11.054

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	13.02	%
Inhibition	=	24.73	%
Inhibition	=	13.02	%
Inhibition	=	13.02	%
Inhibition	=	13.02	%
Inhibition	=	13.02	%
Inhibition	=	13.02	%
Inhibition	=	13.02	%
Inhibition	=	13.02	%
Inhibition	=	13.02	%
Inhibition	=	13.02	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：RAW264.7

External ID: CHEMBL3379708

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 2
First Page: 266
Last Page: 269
DOI: 10.1016/j.bmcl.2014.11.054

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Dose-dependent effect
Inhibition	%	Dose-dependent effect

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：RAW264.7

External ID: CHEMBL3379707

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 2
First Page: 266
Last Page: 269
DOI: 10.1016/j.bmcl.2014.11.054

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active
Inhibition	%	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：RAW264.7

External ID: CHEMBL3379709

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 2
First Page: 266
Last Page: 269
DOI: 10.1016/j.bmcl.2014.11.054

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Dose-dependent effect
Inhibition	%	Dose-dependent effect

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Xanthine dehydrogenase/oxidase

External ID: CHEMBL1015630

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1988
Volume: 51
Issue: 2
First Page: 345
Last Page: 348
DOI: 10.1021/np50056a030

Target ChEMBL ID: CHEMBL3649
ChEMBL Target Name: Xanthine dehydrogenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	0	%
Inhibition	=	0	%
Inhibition	=	85.5	%
Inhibition	=	47.8	%
Inhibition	=	66.9	%
Inhibition	=	17.8	%
Inhibition	=	50.2	%
Inhibition	=	15.4	%
Inhibition	=	0	%
Inhibition	=	67.3	%
Inhibition	=	100	%
Inhibition	=	0.5	%
Inhibition	=	32.1	%
Inhibition	=	47.7	%
Inhibition	=	0	%
Inhibition	=	98.5	%
Inhibition	=	95	%
Inhibition	=	49	%
Inhibition	=	82.9	%
Inhibition	=	22	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL925464

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2007
Volume: 17
Issue: 22
First Page: 6311
Last Page: 6315
DOI: 10.1016/j.bmcl.2007.09.003

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	88.89	%
Activity	=	51.72	%
Activity	=	29.89	%
Activity	=	17.62	%
Activity	=	71.65	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：KB

External ID: CHEMBL1002689

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1979
Volume: 42
Issue: 1
First Page: 85
Last Page: 91
DOI: 10.1021/np50001a002

Target ChEMBL ID: CHEMBL398
ChEMBL Target Name: KB
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	7.4	ug ml-1
ED50	=	6.7	ug ml-1
ED50	=	25	ug ml-1
ED50	=	13	ug ml-1
ED50	=	20	ug ml-1
ED50	=	25	ug ml-1
ED50	=	21	ug ml-1
ED50	>	100	ug ml-1
ED50	=	20	ug ml-1
ED50	=	22	ug ml-1
ED50	=	0.2	ug ml-1
ED50	=	2	ug ml-1
ED50	=	15	ug ml-1
ED50	=	13	ug ml-1
ED50	>	100	ug ml-1
ED50	>	100	ug ml-1
ED50	>	100	ug ml-1
ED50	=	2	ug ml-1
ED50	=	2	ug ml-1
ED50	=	41	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：RAW264.7

External ID: CHEMBL3379702

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 2
First Page: 266
Last Page: 269
DOI: 10.1016/j.bmcl.2014.11.054

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	46.09	%
Inhibition	=	36.55	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：RAW264.7

External ID: CHEMBL3379701

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2015
Volume: 25
Issue: 2
First Page: 266
Last Page: 269
DOI: 10.1016/j.bmcl.2014.11.054

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic

491-50-9 靶点实验数据