HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 4

External ID: CHEMBL4334082

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem
Year: 2019
Volume: 27
Issue: 5
First Page: 800
Last Page: 804
DOI: 10.1016/j.bmc.2019.01.017

Target ChEMBL ID: CHEMBL3729
ChEMBL Target Name: Carbonic anhydrase IV
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
63.8	KA	=	63.8	uM
5.8	KA	=	5.8	uM
3.59	KA	=	3.59	uM
2.4	KA	=	2.4	uM
6.17	KA	=	6.17	uM
4.05	KA	=	4.05	uM
3.14	KA	=	3.14	uM
4.42	KA	=	4.42	uM
0.52	KA	=	0.52	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 2

External ID: CHEMBL4334081

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem
Year: 2019
Volume: 27
Issue: 5
First Page: 800
Last Page: 804
DOI: 10.1016/j.bmc.2019.01.017

Target ChEMBL ID: CHEMBL205
ChEMBL Target Name: Carbonic anhydrase II
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
16.3	KA	=	16.3	uM
7.25	KA	=	7.25	uM
1.62	KA	=	1.62	uM
5.12	KA	=	5.12	uM
0.71	KA	=	0.71	uM
2.8	KA	=	2.8	uM
7.44	KA	=	7.44	uM
15.5	KA	=	15.5	uM
0.6	KA	=	0.6	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 1

External ID: CHEMBL4334080

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem
Year: 2019
Volume: 27
Issue: 5
First Page: 800
Last Page: 804
DOI: 10.1016/j.bmc.2019.01.017

Target ChEMBL ID: CHEMBL261
ChEMBL Target Name: Carbonic anhydrase I
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
8.12	KA	=	8.12	uM
4.89	KA	=	4.89	uM
2.52	KA	=	2.52	uM
21.5	KA	=	21.5	uM
3.76	KA	=	3.76	uM
4.3	KA	=	4.3	uM
3.45	KA	=	3.45	uM
12.7	KA	=	12.7	uM
9.92	KA	=	9.92	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 6

External ID: CHEMBL4334083

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem
Year: 2019
Volume: 27
Issue: 5
First Page: 800
Last Page: 804
DOI: 10.1016/j.bmc.2019.01.017

Target ChEMBL ID: CHEMBL3025
ChEMBL Target Name: Carbonic anhydrase VI
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
2.69	KA	=	2.69	uM
4.26	KA	=	4.26	uM
0.11	KA	=	0.11	uM
0.095	KA	=	0.095	uM
0.26	KA	=	0.26	uM
0.082	KA	=	0.082	uM
0.59	KA	=	0.59	uM
0.38	KA	=	0.38	uM
0.11	KA	=	0.11	uM

4875-43-8 靶点实验数据