HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL966344

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1999
Volume: 62
Issue: 10
First Page: 1385
Last Page: 1389
DOI: 10.1021/np9901581

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity				Not Active
Activity				Not Active
Activity				Not Active
Activity	=	29.8	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL966337

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1999
Volume: 62
Issue: 10
First Page: 1385
Last Page: 1389
DOI: 10.1021/np9901581

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	29	%
Activity	=	28.2	%
Activity	=	30.8	%
Activity	=	29	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Neuronal acetylcholine receptor subunit alpha-4

External ID: CHEMBL1120675

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2010
Volume: 20
Issue: 12
First Page: 3683
Last Page: 3687
DOI: 10.1016/j.bmcl.2010.04.092

Target ChEMBL ID: CHEMBL1907596
ChEMBL Target Name: Neuronal acetylcholine receptor; alpha4/beta2
ChEMBL Target Type: PROTEIN COMPLEX - Target is a defined protein complex, consisting of multiple subunits
Relationship Type: D - Direct protein target assigned
Confidence: Direct protein complex subunits assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.1122	IC50	=	112.2	nM
0.10233	IC50	=	102.33	nM
0.37154	IC50	=	371.54	nM
0.45709	IC50	=	457.09	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL966336

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1999
Volume: 62
Issue: 10
First Page: 1385
Last Page: 1389
DOI: 10.1021/np9901581

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity	=	28.2	%
Activity	=	27.7	%
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL966335

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1999
Volume: 62
Issue: 10
First Page: 1385
Last Page: 1389
DOI: 10.1021/np9901581

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity				Not Determined
Activity	=	27.6	%
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL966346

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1999
Volume: 62
Issue: 10
First Page: 1385
Last Page: 1389
DOI: 10.1021/np9901581

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity				Not Active
Activity				Not Active
Activity	=	24	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL966345

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1999
Volume: 62
Issue: 10
First Page: 1385
Last Page: 1389
DOI: 10.1021/np9901581

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	26.2	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL966347

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 1999
Volume: 62
Issue: 10
First Page: 1385
Last Page: 1389
DOI: 10.1021/np9901581

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity				Active
Activity	=	22.9	%

486-86-2 靶点实验数据