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486-39-5 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Sodium-dependent dopamine transporter
External ID: CHEMBL952559
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 1995
Volume: 58
Issue: 10
First Page: 1475
Last Page: 1484
DOI: 10.1021/np50124a001

Target ChEMBL ID: CHEMBL338
ChEMBL Target Name: Dopamine transporter
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
31.2IC50=31200nM
1IC50=1000nM
0.8IC50=800nM
1.4IC50=1400nM
8.1IC50=8100nM
23.6IC50=23600nM
16.5IC50=16500nM
10.9IC50=10900nM
3.9IC50=3900nM
100IC50>100000nM
31.8IC50=31800nM
46.4IC50=46400nM
46.6IC50=46600nM
13.4IC50=13400nM
41.2IC50=41200nM
56.5IC50=56500nM
85.5IC50=85500nM
100IC50>100000nM
100IC50>100000nM
100IC50>100000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL952561
Protocol: N/A
Comment: Journal: J. Nat. Prod.
Year: 1995
Volume: 58
Issue: 10
First Page: 1475
Last Page: 1484
DOI: 10.1021/np50124a001
Standard TypeStandard RelationStandard Value
Ratio IC50=4
Ratio IC50=274
Ratio IC50>20.4
Ratio IC50=1.9
Ratio IC50>100
Ratio IC50=23.5
Ratio IC50=19.6
Ratio IC50=1.8
Ratio IC50=3.44
Ratio IC50=0.41
Ratio IC50=6.1
Ratio IC50=7.3
Ratio IC50>1.6
Ratio IC50=0.7
Ratio IC50=0.8
Ratio IC50=0.008
Ratio IC50=0.004
Ratio IC50<0.015
Ratio IC50<3.0E-4
Ratio IC50=0.03
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL952560
Protocol: N/A
Comment: Journal: J. Nat. Prod.
Year: 1995
Volume: 58
Issue: 10
First Page: 1475
Last Page: 1484
DOI: 10.1021/np50124a001
Standard TypeStandard RelationStandard Value
Ratio IC50=4.8
Ratio IC50=64
Ratio IC50>20.4
Ratio IC50=2.4
Ratio IC50>100
Ratio IC50=85
Ratio IC50=3.4
Ratio IC50=4.4
Ratio IC50=0.53
Ratio IC50=0.15
Ratio IC50>1.4
Ratio IC50=10
Ratio IC50>1.6
Ratio IC50=3.8
Ratio IC50>3.5
Ratio IC50=0.002
Ratio IC50=0.002
Ratio IC50<0.01
Ratio IC50<6.0E-4
Ratio IC50<0.6