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486-28-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:U-937
External ID: CHEMBL1074620
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2009
Volume: 17
Issue: 18
First Page: 6547
Last Page: 6559
DOI: 10.1016/j.bmc.2009.08.002

Target ChEMBL ID: CHEMBL612794
ChEMBL Target Name: U-937
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
704CC50=704000nM
790CC50=790000nM
2000CC50>2000000nM
2000CC50>2000000nM
535CC50=535000nM
252CC50=252000nM
2000CC50>2000000nM
2000CC50>2000000nM
2000CC50>2000000nM
266CC50=266000nM
420CC50=420000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:U-937
External ID: CHEMBL1065376
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2009
Volume: 17
Issue: 18
First Page: 6547
Last Page: 6559
DOI: 10.1016/j.bmc.2009.08.002

Target ChEMBL ID: CHEMBL612794
ChEMBL Target Name: U-937
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
400IC50>400000nMOutside typical range
182.1IC50=182100nMOutside typical range
400IC50>400000nMOutside typical range
400IC50>400000nMOutside typical range
177.3IC50=177300nMOutside typical range
2.2IC50=2200nM
400IC50>400000nMOutside typical range
255.4IC50=255400nMOutside typical range
400IC50>400000nMOutside typical range
3.5IC50=3500nM
191.9IC50=191900nMOutside typical range