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477-62-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Entamoeba histolytica
External ID: CHEMBL3058937
Protocol: N/A
Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 9
First Page: 2501
Last Page: 2516
DOI: 10.1007/s00044-011-9767-1

Target ChEMBL ID: CHEMBL612853
ChEMBL Target Name: Entamoeba histolytica
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
IC50=12.7ug.mL-1
IC50=114.3ug.mL-1Outside typical range
IC50=92.24ug.mL-1Outside typical range
IC50=81ug.mL-1Outside typical range
IC50=189.01ug.mL-1Outside typical range
IC50=7.93ug.mL-1
IC50=17.8ug.mL-1
IC50=12.7ug.mL-1
IC50=6.89ug.mL-1
IC50=0.00777ug.mL-1
IC50=22.6ug.mL-1
IC50=115.21ug.mL-1Outside typical range
IC50=158.67ug.mL-1Outside typical range
IC50=70.3ug.mL-1Outside typical range
IC50=0.306ug.mL-1
IC50=16.6ug.mL-1
IC50=23ug.mL-1
IC50=14.8ug.mL-1
IC50=0.14ug.mL-1
IC50=105.3ug.mL-1Outside typical range
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasmodium falciparum
External ID: CHEMBL1177462
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2009
Volume: 17
Issue: 9
First Page: 3229
Last Page: 3256
DOI: 10.1016/j.bmc.2009.02.050

Target ChEMBL ID: CHEMBL364
ChEMBL Target Name: Plasmodium falciparum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
0.23IC50=230nM
IC50>5ug.mL-1
IC50=0.1ug.mL-1
IC50=0.003ug.mL-1
IC50=0.62ug.mL-1
10.3IC50=10300nM
28.3IC50=28300nM
0.353IC50=353nM
IC50=1.5ug.mL-1
IC50=27.73ug.mL-1
IC50=1ug.mL-1
14IC50=14000nM
6.7IC50=6700nM
5.64IC50=5640nM
2.15IC50=2150nM
5.13IC50=5130nM
IC50=3.2ug.mL-1
IC50=5.9ug.mL-1
IC50>20ug.mL-1
IC50=0.85ug.mL-1