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469-36-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Human gammaherpesvirus 4
External ID: CHEMBL905095
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2007
Volume: 70
Issue: 6
First Page: 918
Last Page: 922
DOI: 10.1021/np068044u

Target ChEMBL ID: CHEMBL613124
ChEMBL Target Name: Human gammaherpesvirus 4
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.0094IC50=9.4nM
0.0088IC50=8.8nM
0.0099IC50=9.9nM
0.0094IC50=9.4nM
0.0089IC50=8.9nM
0.0088IC50=8.8nM
0.0081IC50=8.1nM
0.0064IC50=6.4nM
0.0061IC50=6.1nM
0.0067IC50=6.7nM
0.0102IC50=10.2nM
0.0088IC50=8.8nM
0.009IC50=9nM
0.0086IC50=8.6nM
0.0088IC50=8.8nM
0.0101IC50=10.1nM
0.009IC50=9nM
0.0095IC50=9.5nM
0.0067IC50=6.7nM
0.0094IC50=9.4nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Raji
External ID: CHEMBL905096
Protocol: N/A
Comment: Journal: J Nat Prod
Year: 2007
Volume: 70
Issue: 6
First Page: 918
Last Page: 922
DOI: 10.1021/np068044u

Target ChEMBL ID: CHEMBL614628
ChEMBL Target Name: Raji
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Activity=60%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
Activity=70%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL905097
Protocol: N/A
Comment: Journal: J. Nat. Prod.
Year: 2007
Volume: 70
Issue: 6
First Page: 918
Last Page: 922
DOI: 10.1021/np068044u
Standard TypeStandard RelationStandard Value
Activity=1.8
Activity=1.6
Activity=1.7
Activity=2
Activity=1.9
Activity=1.8
Activity=2.1
Activity=2.1
Activity=1.5
Activity=1.8
Activity=1.5
Activity=1.9
Activity=2
Activity=1.9
Activity=2
Activity=1.8
Activity=1.7
Activity=1.5
Activity=1.5
Activity=1.5
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:MCF7
External ID: CHEMBL979214
Protocol: N/A
Comment: Journal: J. Nat. Prod.
Year: 2005
Volume: 68
Issue: 1
First Page: 94
Last Page: 97
DOI: 10.1021/np049889d

Target ChEMBL ID: CHEMBL387
ChEMBL Target Name: MCF7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
42IC50=42000nM
79IC50=79000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Reverse transcriptase/RNaseH
External ID: CHEMBL1786436
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2009
Volume: 17
Issue: 14
First Page: 5238
Last Page: 5246
DOI: 10.1016/j.bmc.2009.05.049

Target ChEMBL ID: CHEMBL247
ChEMBL Target Name: Human immunodeficiency virus type 1 reverse transcriptase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
IC50=1.4ug.mL-1
IC50=2.2ug.mL-1
IC50=1.9ug.mL-1
IC50=2.1ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Human gammaherpesvirus 4
External ID: CHEMBL905091
Protocol: N/A
Comment: Journal: J Nat Prod
Year: 2007
Volume: 70
Issue: 6
First Page: 918
Last Page: 922
DOI: 10.1021/np068044u

Target ChEMBL ID: CHEMBL613124
ChEMBL Target Name: Human gammaherpesvirus 4
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=21.6%
Inhibition=8.6%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=19.7%
Inhibition=17.6%
Inhibition=2.3%
Inhibition=3.1%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=0%
Inhibition=0%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Human gammaherpesvirus 4
External ID: CHEMBL905092
Protocol: N/A
Comment: Journal: J Nat Prod
Year: 2007
Volume: 70
Issue: 6
First Page: 918
Last Page: 922
DOI: 10.1021/np068044u

Target ChEMBL ID: CHEMBL613124
ChEMBL Target Name: Human gammaherpesvirus 4
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=49.3%
Inhibition=34.2%
Inhibition=30.2%
Inhibition=25.8%
Inhibition=23.2%
Inhibition=31.4%
Inhibition=30.5%
Inhibition=30.6%
Inhibition=20.4%
Inhibition=16.8%
Inhibition=56%
Inhibition=54.7%
Inhibition=24.6%
Inhibition=26.4%
Inhibition=21.1%
Inhibition=20%
Inhibition=19.1%
Inhibition=26.8%
Inhibition=26.5%
Inhibition=32.4%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Human gammaherpesvirus 4
External ID: CHEMBL905093
Protocol: N/A
Comment: Journal: J Nat Prod
Year: 2007
Volume: 70
Issue: 6
First Page: 918
Last Page: 922
DOI: 10.1021/np068044u

Target ChEMBL ID: CHEMBL613124
ChEMBL Target Name: Human gammaherpesvirus 4
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=76.3%
Inhibition=82.1%
Inhibition=70.2%
Inhibition=69.9%
Inhibition=68.1%
Inhibition=72.8%
Inhibition=71.3%
Inhibition=70%
Inhibition=68.3%
Inhibition=60%
Inhibition=84.7%
Inhibition=82%
Inhibition=71.3%
Inhibition=73.5%
Inhibition=69.7%
Inhibition=67.2%
Inhibition=66.8%
Inhibition=72.6%
Inhibition=68.1%
Inhibition=73.5%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Human gammaherpesvirus 4
External ID: CHEMBL905094
Protocol: N/A
Comment: Journal: J Nat Prod
Year: 2007
Volume: 70
Issue: 6
First Page: 918
Last Page: 922
DOI: 10.1021/np068044u

Target ChEMBL ID: CHEMBL613124
ChEMBL Target Name: Human gammaherpesvirus 4
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Inhibition=100%
Inhibition=100%
Inhibition=95%
Inhibition=93.5%
Inhibition=91.4%
Inhibition=95.2%
Inhibition=94.5%
Inhibition=93.6%
Inhibition=87%
Inhibition=87.4%
Inhibition=100%
Inhibition=100%
Inhibition=92.6%
Inhibition=96.1%
Inhibition=91.2%
Inhibition=90.1%
Inhibition=88.4%
Inhibition=93.8%
Inhibition=94.8%
Inhibition=96.2%