HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL642571

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 1998
Volume: 8
Issue: 5
First Page: 515
Last Page: 520
DOI: 10.1016/s0960-894x(98)00059-6

Standard Type	Standard Relation	Standard Value
pKa4	=	7.71
pKa4	=	8.53
pKa4	=	7.49

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL642775

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 1998
Volume: 8
Issue: 5
First Page: 515
Last Page: 520
DOI: 10.1016/s0960-894x(98)00059-6

Standard Type	Standard Relation	Standard Value
pKa3	=	7.11
pKa3	=	7.1
pKa3	=	7.03

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Phosphoglycerate kinase 1

External ID: CHEMBL825022

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 1998
Volume: 8
Issue: 5
First Page: 515
Last Page: 520
DOI: 10.1016/s0960-894x(98)00059-6

Target ChEMBL ID: CHEMBL2096677
ChEMBL Target Name: Phosphoglycerate kinase
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
163	IC50	=	163000	nM	Outside typical range
1.08	IC50	=	1080	nM
0.88	IC50	=	880	nM

4546-06-9 靶点实验数据