HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3280549

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1977
Volume: 20
Issue: 3
First Page: 439
Last Page: 447
DOI: 10.1021/jm00213a023

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	3.34	10'-10mol/min
Activity	=	2.94	10'-10mol/min
Activity	=	3.03	10'-10mol/min
Activity	=	3.76	10'-10mol/min
Activity	=	0.92	10'-10mol/min
Activity	=	3.35	10'-10mol/min
Activity	=	3.31	10'-10mol/min
Activity	=	4.92	10'-10mol/min
Activity	=	3.75	10'-10mol/min
Activity	=	1.84	10'-10mol/min
Activity	=	2.95	10'-10mol/min

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Albumin

External ID: CHEMBL3280537

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1977
Volume: 20
Issue: 3
First Page: 439
Last Page: 447
DOI: 10.1021/jm00213a023

Target ChEMBL ID: CHEMBL3253
ChEMBL Target Name: Serum albumin
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value
log(PB)	=	1.57
log(PB)	=	1.27
log(PB)	=	1.89
log(PB)	=	1.26
log(PB)	=	1.16
log(PB)	=	1.63
log(PB)	=	1.76
log(PB)	=	1.56
log(PB)	=	0.45
log(PB)	=	1.33
log(PB)	=	1.27
log(PB)	=	1.36
log(PB)	=	1.67
log(PB)	=	1.37
log(PB)	=	1.82
log(PB)	=	1.68
log(PB)	=	0.95
log(PB)	=	1.92
log(PB)	=	1.89
log(PB)	=	1.81

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3280539

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1977
Volume: 20
Issue: 3
First Page: 439
Last Page: 447
DOI: 10.1021/jm00213a023

Standard Type	Standard Relation	Standard Value
Rm	=	1.21
Rm	=	1.92
Rm	=	3.11
Rm	=	1.73
Rm	=	1.68
Rm	=	4.25
Rm	=	3.25
Rm	=	2.7
Rm	=	2.85
Rm	=	1.31
Rm	=	2.3
Rm	=	1.62
Rm	=	2.17
Rm	=	2.38
Rm	=	1.6
Rm	=	2.95
Rm	=	2.85
Rm	=	2.38
Rm	=	1.66

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3280541

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1977
Volume: 20
Issue: 3
First Page: 439
Last Page: 447
DOI: 10.1021/jm00213a023

Standard Type	Standard Relation	Standard Value
pKa	=	3.52
pKa	=	4.59
pKa	=	3.96
pKa	=	5.04
pKa	=	4.83
pKa	=	5.01
pKa	=	5.4
pKa	=	5.37
pKa	=	5.17
pKa	=	5.1
pKa	=	5.09
pKa	=	2.78
pKa	=	4.13
pKa	=	3.88
pKa	=	3.69
pKa	=	4.34
pKa	=	4.62
pKa	=	4.52
pKa	=	4.84
pKa	=	4.34

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Escherichia coli

External ID: CHEMBL3280540

Protocol: N/A

Comment: Journal: J Med Chem
Year: 1977
Volume: 20
Issue: 3
First Page: 439
Last Page: 447
DOI: 10.1021/jm00213a023

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ID50	=	25	umol/L
ID50	=	85	umol/L
ID50	=	130	umol/L
ID50	=	100	umol/L
ID50	=	30	umol/L
ID50	=	125	umol/L
ID50	=	25	umol/L
ID50	=	90	umol/L
ID50	=	125	umol/L
ID50	=	135	umol/L
ID50	=	130	umol/L
ID50	=	120	umol/L
ID50	=	100	umol/L
ID50	=	125	umol/L
ID50	=	45	umol/L
ID50	=	8	umol/L
ID50	=	105	umol/L
ID50	=	120	umol/L
ID50	=	120	umol/L
ID50	=	190	umol/L

446-31-1 靶点实验数据