HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL699277

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2002
Volume: 12
Issue: 18
First Page: 2523
Last Page: 2526
DOI: 10.1016/s0960-894x(02)00505-x

Standard Type	Standard Relation	Standard Value	Standard Units
Rate constant (k)	=	5.3	Ie3 M-1 s-1
Rate constant (k)	=	3.9	Ie3 M-1 s-1
Rate constant (k)	=	3.8	Ie3 M-1 s-1
Rate constant (k)	=	88	Ie3 M-1 s-1
Rate constant (k)	=	46	Ie3 M-1 s-1
Rate constant (k)	=	41	Ie3 M-1 s-1
Rate constant (k)	=	0.1	Ie3 M-1 s-1
Rate constant (k)	=	0.3	Ie3 M-1 s-1
Rate constant (k)	=	1.4	Ie3 M-1 s-1
Rate constant (k)	=	0.6	Ie3 M-1 s-1
Rate constant (k)	=	0.9	Ie3 M-1 s-1
Rate constant (k)	=	1.4	Ie3 M-1 s-1
Rate constant (k)	=	3.7	Ie3 M-1 s-1
Rate constant (k)	=	1.8	Ie3 M-1 s-1
Rate constant (k)	=	1.7	Ie3 M-1 s-1
Rate constant (k)	=	7.5	Ie3 M-1 s-1
Rate constant (k)	=	1	Ie3 M-1 s-1
Rate constant (k)	=	0.9	Ie3 M-1 s-1
Rate constant (k)	=	22	Ie3 M-1 s-1
Rate constant (k)	=	21	Ie3 M-1 s-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：V79

External ID: CHEMBL818633

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2002
Volume: 12
Issue: 18
First Page: 2523
Last Page: 2526
DOI: 10.1016/s0960-894x(02)00505-x

Target ChEMBL ID: CHEMBL614074
ChEMBL Target Name: V79
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Surviving fraction	=	1
Surviving fraction	=	1
Surviving fraction	=	0.01
Surviving fraction	=	0.004
Surviving fraction	=	1
Surviving fraction	=	1
Surviving fraction	=	1
Surviving fraction	<	1.0E-5
Surviving fraction	=	1
Surviving fraction	=	1
Surviving fraction	=	1
Surviving fraction	=	4.0E-5
Surviving fraction	=	0.003
Surviving fraction	=	0.01
Surviving fraction	=	0.04
Surviving fraction	=	0.01
Surviving fraction	=	4.0E-5
Surviving fraction	<	1.0E-5
Surviving fraction	=	9.0E-5
Surviving fraction	=	1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL893762

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2007
Volume: 15
Issue: 13
First Page: 4595
Last Page: 4600
DOI: 10.1016/j.bmc.2007.04.005

Standard Type	Standard Relation	Standard Value
log K	=	1.42
log K	=	1.72
log K	=	1.99
log K	=	1.72
log K	=	2.13
log K	=	3.29
log K	=	2.32
log K	=	2.38
log K	=	1.87
log K	=	2.14
log K	=	1.74
log K	=	2.57
log K	=	2.41
log K	=	1.66
log K	=	1.23
log K	=	3.2
log K	=	2.09
log K	=	2.56
log K	=	1.84
log K	=	2.33

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Albumin

External ID: CHEMBL894775

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2007
Volume: 15
Issue: 13
First Page: 4595
Last Page: 4600
DOI: 10.1016/j.bmc.2007.04.005

Target ChEMBL ID: CHEMBL3253
ChEMBL Target Name: Serum albumin
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value
logKA	=	0.102
logKA	=	-0.04
logKA	=	0.217
logKA	=	0.261
logKA	=	0.458
logKA	=	1.082
logKA	=	0.623
logKA	=	0.646
logKA	=	0.243
logKA	=	0.228
logKA	=	0.308
logKA	=	0.808
logKA	=	0.863
logKA	=	0.305
logKA	=	0.185
logKA	=	1.186
logKA	=	0.031
logKA	=	0.15
logKA	=	0.155
logKA	=	0.393

443-75-4 靶点实验数据