HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1247378

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2010
Volume: 53
Issue: 17
First Page: 6301
Last Page: 6315
DOI: 10.1021/jm100337z

Standard Type	Standard Relation	Standard Value
Ratio IC50	=	40
Ratio IC50	=	40
Ratio IC50	=	16
Ratio IC50	=	190
Ratio IC50	=	140
Ratio IC50	=	50

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1247377

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2010
Volume: 53
Issue: 17
First Page: 6301
Last Page: 6315
DOI: 10.1021/jm100337z

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
1.99526	IC50	=	1995.26	nM
28.1838	IC50	=	28183.83	nM
1.8197	IC50	=	1819.7	nM
6.0256	IC50	=	6025.6	nM
8.91251	IC50	=	8912.51	nM
38.0189	IC50	=	38018.94	nM
22.9087	IC50	=	22908.68	nM
20.893	IC50	=	20892.96	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Membrane primary amine oxidase

External ID: CHEMBL1247376

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2010
Volume: 53
Issue: 17
First Page: 6301
Last Page: 6315
DOI: 10.1021/jm100337z

Target ChEMBL ID: CHEMBL3437
ChEMBL Target Name: Amine oxidase, copper containing
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.08913	IC50	=	89.13	nM
0.19953	IC50	=	199.53	nM
0.26915	IC50	=	269.15	nM
0.34674	IC50	=	346.74	nM
0.06457	IC50	=	64.57	nM
0.32359	IC50	=	323.59	nM
0.26915	IC50	=	269.15	nM
0.30903	IC50	=	309.03	nM

4397-11-9 靶点实验数据