HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Genome polyprotein

External ID: CHEMBL5109290

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 240
First Page: 114576
Last Page: 114576
DOI: 10.1016/j.ejmech.2022.114576

Target ChEMBL ID: CHEMBL5980
ChEMBL Target Name: Genome polyprotein
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	67	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Genome polyprotein

External ID: CHEMBL5109291

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 240
First Page: 114576
Last Page: 114576
DOI: 10.1016/j.ejmech.2022.114576

Target ChEMBL ID: CHEMBL5980
ChEMBL Target Name: Genome polyprotein
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
8.24	IC50	=	8240	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bos taurus

External ID: CHEMBL653386

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 1993
Volume: 3
Issue: 12
First Page: 2875
Last Page: 2878
DOI: 10.1016/S0960-894X(01)80782-4

Target ChEMBL ID: CHEMBL613489
ChEMBL Target Name: Bos taurus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
3	IC50	=	3000	nM
3	IC50	=	3000	nM
13	IC50	=	13000	nM
10	IC50	=	10000	nM
9	IC50	=	9000	nM
17	IC50	=	17000	nM
30	IC50	>	30000	nM
3	IC50	=	3000	nM
18.2	IC50	=	18200	nM
30	IC50	>	30000	nM
13.5	IC50	=	13500	nM
5	IC50	=	5000	nM
30	IC50	>	30000	nM
28	IC50	=	28000	nM
30	IC50	>	30000	nM

4322-98-9 靶点实验数据