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42979-83-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Steryl-sulfatase
External ID: CHEMBL1839049
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2011
Volume: 19
Issue: 20
First Page: 5999
Last Page: 6005
DOI: 10.1016/j.bmc.2011.08.046

Target ChEMBL ID: CHEMBL3559
ChEMBL Target Name: Steryl-sulfatase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
IC50Not Determined
26IC50=26000nM
224IC50=224000nMOutside typical range
Inhibition%Not Active
Inhibition%Dose-dependent effect
6.7IC50=6700nM
Inhibition%Not Active