HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3106989

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2014
Volume: 22
Issue: 3
First Page: 1121
Last Page: 1127
DOI: 10.1016/j.bmc.2013.12.020

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	CC50	=	10000	nM
51	CC50	=	51000	nM
70.5	CC50	=	70500	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Trypanosoma cruzi

External ID: CHEMBL3106990

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2014
Volume: 22
Issue: 3
First Page: 1121
Last Page: 1127
DOI: 10.1016/j.bmc.2013.12.020

Target ChEMBL ID: CHEMBL368
ChEMBL Target Name: Trypanosoma cruzi
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	EC50	>	100000	nM
100	EC50	>	100000	nM
100	EC50	>	100000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Trypanosoma cruzi

External ID: CHEMBL3106991

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2014
Volume: 22
Issue: 3
First Page: 1121
Last Page: 1127
DOI: 10.1016/j.bmc.2013.12.020

Target ChEMBL ID: CHEMBL368
ChEMBL Target Name: Trypanosoma cruzi
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
25.1	IC50	=	25100	nM
14.3	IC50	=	14300	nM
82.2	IC50	=	82200	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Leishmania amazonensis

External ID: CHEMBL3106992

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2014
Volume: 22
Issue: 3
First Page: 1121
Last Page: 1127
DOI: 10.1016/j.bmc.2013.12.020

Target ChEMBL ID: CHEMBL612877
ChEMBL Target Name: Leishmania amazonensis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
20.5	IC50	=	20500	nM
20.4	IC50	=	20400	nM
100	IC50	>	100000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：LLC-MK2

External ID: CHEMBL3106988

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2014
Volume: 22
Issue: 3
First Page: 1121
Last Page: 1127
DOI: 10.1016/j.bmc.2013.12.020

Target ChEMBL ID: CHEMBL614691
ChEMBL Target Name: LLC-MK2
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
314.3	CC50	=	314300	nM
93	CC50	=	93000	nM
266	CC50	=	266000	nM

42968-14-9 靶点实验数据