HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A

External ID: CHEMBL616344

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1996
Volume: 39
Issue: 1
First Page: 126
Last Page: 134
DOI: 10.1021/jm950410b

Target ChEMBL ID: CHEMBL273
ChEMBL Target Name: Serotonin 1a (5-HT1a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
10	Ki	=	10000	nM
0.16982	Ki	=	169.82	nM
2.51189	Ki	=	2511.89	nM
0.01072	Ki	=	10.72	nM
0.004786	Ki	=	4.786	nM
0.01995	Ki	=	19.95	nM
0.001862	Ki	=	1.862	nM
6.026E-4	Ki	=	0.6026	nM
0.39811	Ki	=	398.11	nM
0.14454	Ki	=	144.54	nM
0.01288	Ki	=	12.88	nM
0.6166	Ki	=	616.6	nM
0.02188	Ki	=	21.88	nM
1.0E-4	Ki	=	0.1	nM
0.00263	Ki	=	2.63	nM
0.02512	Ki	=	25.12	nM
0.07943	Ki	=	79.43	nM
0.002399	Ki	=	2.399	nM
0.09333	Ki	=	93.33	nM
50.1187	Ki	=	50118.72	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A

External ID: CHEMBL615962

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1988
Volume: 31
Issue: 10
First Page: 1968
Last Page: 1971
DOI: 10.1021/jm00118a018

Target ChEMBL ID: CHEMBL273
ChEMBL Target Name: Serotonin 1a (5-HT1a) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.068	Ki	=	68	nM
0.38	Ki	=	380	nM
2.9	Ki	=	2900	nM
1.52	Ki	=	1520	nM
0.036	Ki	=	36	nM
0.01	Ki	=	10	nM
0.06	Ki	=	60	nM
0.002	Ki	=	2	nM
6	Ki	>	6000	nM
0.001	Ki	=	1	nM
1.41	Ki	=	1410	nM

40255-41-2 靶点实验数据