HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：L6

External ID: CHEMBL707345

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2004
Volume: 47
Issue: 9
First Page: 2296
Last Page: 2307
DOI: 10.1021/jm031024u

Target ChEMBL ID: CHEMBL614793
ChEMBL Target Name: L6
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
2.35	IC50		2350	nM
0.63	IC50	=	630	nM
19.6	IC50		19600	nM
2.7	IC50		2700	nM
116	IC50	=	116000	nM	Outside typical range
56.4	IC50		56400	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：L6

External ID: CHEMBL852824

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2004
Volume: 47
Issue: 9
First Page: 2296
Last Page: 2307
DOI: 10.1021/jm031024u

Target ChEMBL ID: CHEMBL614793
ChEMBL Target Name: L6
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Ratio	>	152
Ratio	=	22
Ratio	=	3456
Ratio	>	9.4
Ratio	>	37
Ratio	=	1.8
Ratio	=	17.4

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Trypanosoma brucei rhodesiense

External ID: CHEMBL814902

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 2004
Volume: 47
Issue: 9
First Page: 2296
Last Page: 2307
DOI: 10.1021/jm031024u

Target ChEMBL ID: CHEMBL612348
ChEMBL Target Name: Trypanosoma brucei rhodesiense
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.107	IC50	=	107	nM
0.047	IC50	=	47	nM
4.3	IC50	=	4300	nM
30.3	IC50	=	30300	nM
1.4	IC50	=	1400	nM
11	IC50	=	11000	nM
3.1	IC50	=	3100	nM
84.4	IC50	=	84400	nM
16.1	IC50	=	16100	nM
32.4	IC50	=	32400	nM
0.161	IC50	=	161	nM
21.4	IC50	=	21400	nM
0.22	IC50	=	220	nM

3988-03-2 靶点实验数据