HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HT-29

External ID: CHEMBL938757

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1991
Volume: 54
Issue: 6
First Page: 1656
Last Page: 1660
DOI: 10.1021/np50078a027

Target ChEMBL ID: CHEMBL384
ChEMBL Target Name: HT-29
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	2.65	ug ml-1
ED50	>	25	ug ml-1
ED50	=	4.71	ug ml-1
ED50	=	4.18	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	3.47	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：MCF7

External ID: CHEMBL938756

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1991
Volume: 54
Issue: 6
First Page: 1656
Last Page: 1660
DOI: 10.1021/np50078a027

Target ChEMBL ID: CHEMBL387
ChEMBL Target Name: MCF7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	3.71	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	6.93	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Malme-3M

External ID: CHEMBL942437

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1991
Volume: 54
Issue: 6
First Page: 1656
Last Page: 1660
DOI: 10.1021/np50078a027

Target ChEMBL ID: CHEMBL614021
ChEMBL Target Name: Malme-3M
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	24.09	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	4.8	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	10	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：SK-MEL

External ID: CHEMBL938758

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1991
Volume: 54
Issue: 6
First Page: 1656
Last Page: 1660
DOI: 10.1021/np50078a027

Target ChEMBL ID: CHEMBL614914
ChEMBL Target Name: SK-MEL
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	8.18	ug ml-1
ED50	=	2.03	ug ml-1
ED50	=	21.03	ug ml-1
ED50	=	6.59	ug ml-1
ED50	=	3.66	ug ml-1
ED50	=	5.11	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	3.09	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL938755

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1991
Volume: 54
Issue: 6
First Page: 1656
Last Page: 1660
DOI: 10.1021/np50078a027

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	2.72	ug ml-1
ED50	=	5.07	ug ml-1
ED50	=	8.87	ug ml-1
ED50	=	4.65	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	>	25	ug ml-1
ED50	=	3.24	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Tyrosine-protein kinase Lck

External ID: CHEMBL819754

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1991
Volume: 34
Issue: 2
First Page: 798
Last Page: 806
DOI: 10.1021/jm00106a047

Target ChEMBL ID: CHEMBL258
ChEMBL Target Name: Tyrosine-protein kinase LCK
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
504	IC50	=	504000	nM	Outside typical range
1160	IC50	=	1160000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
1032	IC50	=	1032000	nM	Outside typical range
1595	IC50	=	1595000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
1.2	IC50	=	1200	nM
2000	IC50	>	2000000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
138	IC50	=	138000	nM	Outside typical range
2000	IC50	>	2000000	nM	Outside typical range
810	IC50	=	810000	nM	Outside typical range

39679-60-2 靶点实验数据