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3886-80-4 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Epoxide hydrolase 1
External ID: CHEMBL4686507
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2020
Volume: 193
First Page: 112206
Last Page: 112206
DOI: 10.1016/j.ejmech.2020.112206

Target ChEMBL ID: CHEMBL1968
ChEMBL Target Name: Epoxide hydrolase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.019IC50=19nM
0.01IC50=10nM
1.466IC50=1466nM
20IC50=20000nM
0.028IC50=28nM
0.0022IC50=2.2nM
53IC50=53000nM
72IC50=72000nM
0.15IC50=150nM
50IC50>50000nM
0.422IC50=422nM
0.032IC50=32nM
0.193IC50=193nM
0.11IC50=110nM
42IC50=42000nM
0.14IC50=140nM
55IC50=55000nM
100IC50>100000nM
87IC50=87000nM
0.399IC50=399nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Epoxide hydrolase 1
External ID: CHEMBL4686508
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 193
First Page: 112206
Last Page: 112206
DOI: 10.1016/j.ejmech.2020.112206

Target ChEMBL ID: CHEMBL1968
ChEMBL Target Name: Epoxide hydrolase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
Inhibition=83%
Inhibition=0%
Inhibition=67%
Inhibition=80%
Inhibition=25%