前往化源商城

38176-02-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Homo sapiens
External ID: CHEMBL876052
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102

Target ChEMBL ID: CHEMBL372
ChEMBL Target Name: Homo sapiens
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard Value
Peff=0.2
Peff=0.04
Peff=0.05
Peff=0.2
Peff=7.8
Peff=4.3
Peff=0.2
Peff=4.5
Peff=8.3
Peff=6.2
Peff=0.3
Peff=3.4
Peff=8.4
Peff=0.3
Peff=1.3
Peff=2.9
Peff=4.4
Peff=0.3
Peff=10
Peff=6.7
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL636382
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102
Standard TypeStandard RelationStandard Value
Log Pion=0.96
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL636358
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102
Standard TypeStandard RelationStandard Value
LogP=3.96
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL857877
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102
Standard TypeStandard RelationStandard Value
LogD5.5<-2
LogD5.5=-1
LogD5.5=2.1
LogD5.5=-1.6
LogD5.5<-2
LogD5.5<-2
LogD5.5=-0.6
LogD5.5=-1.3
LogD5.5=1.2
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL641756
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102
Standard TypeStandard RelationStandard Value
LogD6.5<-2
LogD6.5=-1
LogD6.5=1.1
LogD6.5=-1.6
LogD6.5<-2
LogD6.5<-2
LogD6.5=-0.5
LogD6.5=-1.3
LogD6.5=1.9
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL640127
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102
Standard TypeStandard RelationStandard Value
LogD7.4<-2
LogD7.4=-1
LogD7.4=0.3
LogD7.4=-1.6
LogD7.4<-2
LogD7.4<-2
LogD7.4=0
LogD7.4=-1.1
LogD7.4=2.7
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL875940
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102
Standard TypeStandard RelationStandard Value
pKa=8.66
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL633120
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102
Standard TypeStandard RelationStandard Value
GOF=0.6
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL623856
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 25
First Page: 4939
Last Page: 4949
DOI: 10.1021/jm9810102
Standard TypeStandard RelationStandard Value
CLogP=-0.11
CLogP=-0.15
CLogP=2.29
CLogP=-2.61
CLogP=1.98
CLogP=0.01
CLogP=0.19
CLogP=2.82
CLogP=-1.54
CLogP=-2.92
CLogP=2.79
CLogP=0.33
CLogP=1.2
CLogP=2.75
CLogP=4.09
CLogP=0.48
CLogP=3.53