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375357-96-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:5-hydroxytryptamine receptor 2B
External ID: CHEMBL909200
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2006
Volume: 16
Issue: 18
First Page: 4830
Last Page: 4833
DOI: 10.1016/j.bmcl.2006.06.068

Target ChEMBL ID: CHEMBL1833
ChEMBL Target Name: Serotonin 2b (5-HT2b) receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
0.03IC50=30nM
10IC50>10000nM
0.856IC50=856nM
0.5IC50=500nM
0.542IC50=542nM
5IC50=5000nM
0.092IC50=92nM
0.188IC50=188nM
0.28IC50=280nM
0.426IC50=426nM
0.1IC50=100nM
1.281IC50=1281nM
ActivityNot Active