HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_2153_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	Standard Relation	PubChem Standard Value	Ki Qualifier	Ki	Target Accession(s)	Ligand	Target
Ki		0.052		52	P50579	BDBM17449	Methionine aminopeptidase 2
Ki		0.28		280	P50579	BDBM17450	Methionine aminopeptidase 2
Ki		0.112		112	P50579	BDBM17452	Methionine aminopeptidase 2
Ki	>	1	>	1000	P50579	BDBM17454	Methionine aminopeptidase 2
Ki		0.03		30	P50579	BDBM17455	Methionine aminopeptidase 2
Ki	>	1	>	1000	P50579	BDBM17456	Methionine aminopeptidase 2
Ki		0.337		337	P50579	BDBM17458	Methionine aminopeptidase 2
Ki		0.003		3	P50579	BDBM17460	Methionine aminopeptidase 2
Ki		0.001		1	P50579	BDBM17461	Methionine aminopeptidase 2
Ki		0.018		18	P50579	BDBM17462	Methionine aminopeptidase 2
Ki		0.3		300	P50579	BDBM17463	Methionine aminopeptidase 2
Ki		0.029		29	P50579	BDBM17465	Methionine aminopeptidase 2
Ki		0.016		16	P50579	BDBM17466	Methionine aminopeptidase 2
Ki		0.004		4	P50579	BDBM17467	Methionine aminopeptidase 2
Ki		0.013		13	P50579	BDBM17469	Methionine aminopeptidase 2
Ki		0.041		41	P50579	BDBM17470	Methionine aminopeptidase 2
Ki		0.26		260	P50579	BDBM17471	Methionine aminopeptidase 2
Ki	>	1	>	1000	P50579	BDBM17472	Methionine aminopeptidase 2
Ki		0.006		6	P50579	BDBM17473	Methionine aminopeptidase 2
Ki		0.003		3	P50579	BDBM17474	Methionine aminopeptidase 2

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Methionine aminopeptidase 2

External ID: CHEMBL884825

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 18
First Page: 5644
Last Page: 5647
DOI: 10.1021/jm050408c

Target ChEMBL ID: CHEMBL3922
ChEMBL Target Name: Methionine aminopeptidase 2
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	=	26	%

369363-80-4 靶点实验数据