HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：J774.A1

External ID: CHEMBL5333239

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2023
Volume: 246
First Page: 114996
Last Page: 114996
DOI: 10.1016/j.ejmech.2022.114996

Target ChEMBL ID: CHEMBL614040
ChEMBL Target Name: J774.A1
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
42.11	CC50	=	42110	nM
42.25	CC50	=	42250	nM
41.1	CC50	=	41100	nM
44.15	CC50	=	44150	nM
50.53	CC50	=	50530	nM
42.4	CC50	=	42400	nM
39	CC50	=	39000	nM
42.1	CC50	=	42100	nM
38.75	CC50	=	38750	nM
52.35	CC50	=	52350	nM
	CC50				Not Determined
	CC50				Not Determined
46.65	CC50	=	46650	nM
51.2	CC50	=	51200	nM
	CC50				Not Determined
46.46	CC50	=	46460	nM
	CC50				Not Determined
	CC50				Not Determined
	CC50				Not Determined
42.8	CC50	=	42800	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Vero

External ID: CHEMBL5333240

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2023
Volume: 246
First Page: 114996
Last Page: 114996
DOI: 10.1016/j.ejmech.2022.114996

Target ChEMBL ID: CHEMBL391
ChEMBL Target Name: Vero
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
3.058	CC50	=	3058	nM
7.09	CC50	=	7090	nM
65.22	CC50	=	65220	nM
3.17	CC50	=	3170	nM
13.87	CC50	=	13870	nM
155.84	CC50	=	155840	nM
16.31	CC50	=	16310	nM
7.29	CC50	=	7290	nM
6.49	CC50	=	6490	nM
14.5	CC50	=	14500	nM
	CC50				Not Determined
	CC50				Not Determined
2.54	CC50	=	2540	nM
10.6	CC50	=	10600	nM
	CC50				Not Determined
13.16	CC50	=	13160	nM
	CC50				Not Determined
	CC50				Not Determined
	CC50				Not Determined
11.72	CC50	=	11720	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Leishmania donovani

External ID: CHEMBL5333238

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2023
Volume: 246
First Page: 114996
Last Page: 114996
DOI: 10.1016/j.ejmech.2022.114996

Target ChEMBL ID: CHEMBL367
ChEMBL Target Name: Leishmania donovani
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
3.68	IC50	=	3680	nM
7.97	IC50	=	7970	nM
7.47	IC50	=	7470	nM
3.47	IC50	=	3470	nM
4.62	IC50	=	4620	nM
7.71	IC50	=	7710	nM
2.09	IC50	=	2090	nM
3.27	IC50	=	3270	nM
3.83	IC50	=	3830	nM
2.89	IC50	=	2890	nM
	IC50				Not Active
	IC50				Not Active
3.5	IC50	=	3500	nM
3.54	IC50	=	3540	nM
	IC50				Not Active
2.62	IC50	=	2620	nM
	IC50				Not Active
	IC50				Not Active
	IC50				Not Active
4.06	IC50	=	4060	nM

369-74-4 靶点实验数据