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36735-22-5 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL1292026
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2010
Volume: 20
Issue: 24
First Page: 7312
Last Page: 7316
DOI: 10.1016/j.bmcl.2010.10.068
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
395Solubility=395000nM
500Solubility>500000nM
500Solubility>500000nM
420Solubility>420000nM
30.2Solubility=30200nM
120Solubility=120000nM
500Solubility>500000nM
500Solubility>500000nM
459Solubility>459000nM
500Solubility>500000nM
407Solubility>407000nM
444Solubility>444000nM
500Solubility>500000nM
429Solubility=429000nM
18.1Solubility=18100nM
500Solubility>500000nM
54Solubility=54000nM
2.1Solubility=2100nM
500Solubility>500000nM
500Solubility>500000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137727
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (choleostasis)=3references out of a total of 9
Hepatotoxicity (choleostasis)=3references out of a total of 5
Hepatotoxicity (choleostasis)=2references out of a total of 15
Hepatotoxicity (choleostasis)=10references out of a total of 15
Hepatotoxicity (choleostasis)=0references out of a total of 6
Hepatotoxicity (choleostasis)=6references out of a total of 31
Hepatotoxicity (choleostasis)=12references out of a total of 33
Hepatotoxicity (choleostasis)=1references out of a total of 2
Hepatotoxicity (choleostasis)=10references out of a total of 33
Hepatotoxicity (choleostasis)=1references out of a total of 33
Hepatotoxicity (choleostasis)=11references out of a total of 69
Hepatotoxicity (choleostasis)=0references out of a total of 1
Hepatotoxicity (choleostasis)=4references out of a total of 58
Hepatotoxicity (choleostasis)=55references out of a total of 90
Hepatotoxicity (choleostasis)=1references out of a total of 5
Hepatotoxicity (choleostasis)=0references out of a total of 1
Hepatotoxicity (choleostasis)=2references out of a total of 6
Hepatotoxicity (choleostasis)=0references out of a total of 4
Hepatotoxicity (choleostasis)=0references out of a total of 8
Hepatotoxicity (choleostasis)=0references out of a total of 16
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137728
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (severe hepatitis)=0references out of a total of 1
Hepatotoxicity (severe hepatitis)=2references out of a total of 69
Hepatotoxicity (severe hepatitis)=0references out of a total of 5
Hepatotoxicity (severe hepatitis)=5references out of a total of 27
Hepatotoxicity (severe hepatitis)=0references out of a total of 13
Hepatotoxicity (severe hepatitis)=0references out of a total of 1
Hepatotoxicity (severe hepatitis)=5references out of a total of 132
Hepatotoxicity (severe hepatitis)=0references out of a total of 23
Hepatotoxicity (severe hepatitis)=0references out of a total of 1
Hepatotoxicity (severe hepatitis)=0references out of a total of 9
Hepatotoxicity (severe hepatitis)=5references out of a total of 34
Hepatotoxicity (severe hepatitis)=1references out of a total of 5
Hepatotoxicity (severe hepatitis)=21references out of a total of 53
Hepatotoxicity (severe hepatitis)=1references out of a total of 1
Hepatotoxicity (severe hepatitis)=1references out of a total of 14
Hepatotoxicity (severe hepatitis)=0references out of a total of 5
Hepatotoxicity (severe hepatitis)=0references out of a total of 3
Hepatotoxicity (severe hepatitis)=1references out of a total of 16
Hepatotoxicity (severe hepatitis)=14references out of a total of 123
Hepatotoxicity (severe hepatitis)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137729
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (chronic liver disease)=0references out of a total of 1
Hepatotoxicity (chronic liver disease)=0references out of a total of 69
Hepatotoxicity (chronic liver disease)=0references out of a total of 5
Hepatotoxicity (chronic liver disease)=0references out of a total of 27
Hepatotoxicity (chronic liver disease)=0references out of a total of 13
Hepatotoxicity (chronic liver disease)=0references out of a total of 1
Hepatotoxicity (chronic liver disease)=1references out of a total of 132
Hepatotoxicity (chronic liver disease)=0references out of a total of 23
Hepatotoxicity (chronic liver disease)=0references out of a total of 1
Hepatotoxicity (chronic liver disease)=0references out of a total of 9
Hepatotoxicity (chronic liver disease)=1references out of a total of 34
Hepatotoxicity (chronic liver disease)=0references out of a total of 5
Hepatotoxicity (chronic liver disease)=1references out of a total of 53
Hepatotoxicity (chronic liver disease)=0references out of a total of 1
Hepatotoxicity (chronic liver disease)=0references out of a total of 14
Hepatotoxicity (chronic liver disease)=0references out of a total of 5
Hepatotoxicity (chronic liver disease)=0references out of a total of 3
Hepatotoxicity (chronic liver disease)=0references out of a total of 16
Hepatotoxicity (chronic liver disease)=6references out of a total of 123
Hepatotoxicity (chronic liver disease)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137730
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (cirrhosis)=0references out of a total of 1
Hepatotoxicity (cirrhosis)=0references out of a total of 69
Hepatotoxicity (cirrhosis)=0references out of a total of 5
Hepatotoxicity (cirrhosis)=0references out of a total of 27
Hepatotoxicity (cirrhosis)=0references out of a total of 13
Hepatotoxicity (cirrhosis)=0references out of a total of 1
Hepatotoxicity (cirrhosis)=0references out of a total of 132
Hepatotoxicity (cirrhosis)=0references out of a total of 23
Hepatotoxicity (cirrhosis)=0references out of a total of 1
Hepatotoxicity (cirrhosis)=0references out of a total of 9
Hepatotoxicity (cirrhosis)=0references out of a total of 34
Hepatotoxicity (cirrhosis)=0references out of a total of 5
Hepatotoxicity (cirrhosis)=0references out of a total of 53
Hepatotoxicity (cirrhosis)=0references out of a total of 1
Hepatotoxicity (cirrhosis)=0references out of a total of 14
Hepatotoxicity (cirrhosis)=0references out of a total of 5
Hepatotoxicity (cirrhosis)=0references out of a total of 3
Hepatotoxicity (cirrhosis)=0references out of a total of 16
Hepatotoxicity (cirrhosis)=0references out of a total of 123
Hepatotoxicity (cirrhosis)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3137731
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 1
Hepatotoxicity (granulomatous hepatitis)=1references out of a total of 69
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 5
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 27
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 13
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 1
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 132
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 23
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 1
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 9
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 34
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 5
Hepatotoxicity (granulomatous hepatitis)=1references out of a total of 53
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 1
Hepatotoxicity (granulomatous hepatitis)=1references out of a total of 14
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 5
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 3
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 16
Hepatotoxicity (granulomatous hepatitis)=5references out of a total of 123
Hepatotoxicity (granulomatous hepatitis)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137732
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (association with vascular disease)=0references out of a total of 1
Hepatotoxicity (association with vascular disease)=0references out of a total of 69
Hepatotoxicity (association with vascular disease)=0references out of a total of 5
Hepatotoxicity (association with vascular disease)=0references out of a total of 27
Hepatotoxicity (association with vascular disease)=0references out of a total of 13
Hepatotoxicity (association with vascular disease)=0references out of a total of 1
Hepatotoxicity (association with vascular disease)=0references out of a total of 132
Hepatotoxicity (association with vascular disease)=0references out of a total of 23
Hepatotoxicity (association with vascular disease)=0references out of a total of 1
Hepatotoxicity (association with vascular disease)=0references out of a total of 9
Hepatotoxicity (association with vascular disease)=0references out of a total of 34
Hepatotoxicity (association with vascular disease)=0references out of a total of 5
Hepatotoxicity (association with vascular disease)=0references out of a total of 53
Hepatotoxicity (association with vascular disease)=0references out of a total of 1
Hepatotoxicity (association with vascular disease)=0references out of a total of 14
Hepatotoxicity (association with vascular disease)=0references out of a total of 5
Hepatotoxicity (association with vascular disease)=0references out of a total of 3
Hepatotoxicity (association with vascular disease)=1references out of a total of 16
Hepatotoxicity (association with vascular disease)=0references out of a total of 123
Hepatotoxicity (association with vascular disease)=2references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137733
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (steatosis)=0references out of a total of 1
Hepatotoxicity (steatosis)=0references out of a total of 69
Hepatotoxicity (steatosis)=0references out of a total of 5
Hepatotoxicity (steatosis)=0references out of a total of 27
Hepatotoxicity (steatosis)=0references out of a total of 13
Hepatotoxicity (steatosis)=0references out of a total of 1
Hepatotoxicity (steatosis)=1references out of a total of 132
Hepatotoxicity (steatosis)=0references out of a total of 23
Hepatotoxicity (steatosis)=0references out of a total of 1
Hepatotoxicity (steatosis)=0references out of a total of 9
Hepatotoxicity (steatosis)=0references out of a total of 34
Hepatotoxicity (steatosis)=0references out of a total of 5
Hepatotoxicity (steatosis)=2references out of a total of 53
Hepatotoxicity (steatosis)=0references out of a total of 1
Hepatotoxicity (steatosis)=0references out of a total of 14
Hepatotoxicity (steatosis)=0references out of a total of 5
Hepatotoxicity (steatosis)=0references out of a total of 3
Hepatotoxicity (steatosis)=0references out of a total of 16
Hepatotoxicity (steatosis)=4references out of a total of 123
Hepatotoxicity (steatosis)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137734
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (malignant tumour)=0references out of a total of 1
Hepatotoxicity (malignant tumour)=0references out of a total of 69
Hepatotoxicity (malignant tumour)=0references out of a total of 5
Hepatotoxicity (malignant tumour)=0references out of a total of 27
Hepatotoxicity (malignant tumour)=0references out of a total of 13
Hepatotoxicity (malignant tumour)=0references out of a total of 1
Hepatotoxicity (malignant tumour)=0references out of a total of 132
Hepatotoxicity (malignant tumour)=0references out of a total of 23
Hepatotoxicity (malignant tumour)=0references out of a total of 1
Hepatotoxicity (malignant tumour)=0references out of a total of 9
Hepatotoxicity (malignant tumour)=0references out of a total of 34
Hepatotoxicity (malignant tumour)=0references out of a total of 5
Hepatotoxicity (malignant tumour)=0references out of a total of 53
Hepatotoxicity (malignant tumour)=0references out of a total of 1
Hepatotoxicity (malignant tumour)=0references out of a total of 14
Hepatotoxicity (malignant tumour)=0references out of a total of 5
Hepatotoxicity (malignant tumour)=0references out of a total of 3
Hepatotoxicity (malignant tumour)=6references out of a total of 16
Hepatotoxicity (malignant tumour)=0references out of a total of 123
Hepatotoxicity (malignant tumour)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3137735
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (benign tumour)=0references out of a total of 1
Hepatotoxicity (benign tumour)=0references out of a total of 69
Hepatotoxicity (benign tumour)=0references out of a total of 5
Hepatotoxicity (benign tumour)=0references out of a total of 27
Hepatotoxicity (benign tumour)=0references out of a total of 13
Hepatotoxicity (benign tumour)=0references out of a total of 1
Hepatotoxicity (benign tumour)=0references out of a total of 132
Hepatotoxicity (benign tumour)=0references out of a total of 23
Hepatotoxicity (benign tumour)=0references out of a total of 1
Hepatotoxicity (benign tumour)=0references out of a total of 9
Hepatotoxicity (benign tumour)=0references out of a total of 34
Hepatotoxicity (benign tumour)=0references out of a total of 5
Hepatotoxicity (benign tumour)=0references out of a total of 53
Hepatotoxicity (benign tumour)=0references out of a total of 1
Hepatotoxicity (benign tumour)=0references out of a total of 14
Hepatotoxicity (benign tumour)=0references out of a total of 5
Hepatotoxicity (benign tumour)=0references out of a total of 3
Hepatotoxicity (benign tumour)=0references out of a total of 16
Hepatotoxicity (benign tumour)=0references out of a total of 123
Hepatotoxicity (benign tumour)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3137736
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeActivity Comment
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)yes
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)yes
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)yes
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)
Hepatotoxicity (animal toxicity known)yes
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137737
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeActivity Comment
Hepatotoxicity (successful reintroduction)yes
Hepatotoxicity (successful reintroduction)yes
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)yes
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
Hepatotoxicity (successful reintroduction)
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137738
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeActivity Comment
Hepatotoxicity (comment)
Hepatotoxicity (comment)I/PYRAZINAMIDE
Hepatotoxicity (comment)
Hepatotoxicity (comment)
Hepatotoxicity (comment)
Hepatotoxicity (comment)
Hepatotoxicity (comment)DUCTOPENIE AC_ANTI-N/-ADN
Hepatotoxicity (comment)AC_ANTI-N
Hepatotoxicity (comment)
Hepatotoxicity (comment)RC/NOMIFENSINE
Hepatotoxicity (comment)RC/DESPRAMINE CHOLESTASE_PROLONGEE
Hepatotoxicity (comment)
Hepatotoxicity (comment)CHOLESTASE_PROLONGEE
Hepatotoxicity (comment)
Hepatotoxicity (comment)AC_ANTI-N/-M #CBP
Hepatotoxicity (comment)ENCEPHALOPATHIE
Hepatotoxicity (comment)
Hepatotoxicity (comment)ANGIOSARCOME RC/TAMOXIFENE
Hepatotoxicity (comment)#MNI CHOLESTASE_PROLONGEE DUCTOPENIE #CBP
Hepatotoxicity (comment)MVO PELIOSE
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3137739
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeActivity Comment
Hepatotoxicity (time to onset)
Hepatotoxicity (time to onset)4 days - 26 weeks
Hepatotoxicity (time to onset)2 weeks
Hepatotoxicity (time to onset)3 days - 10 years
Hepatotoxicity (time to onset)
Hepatotoxicity (time to onset)
Hepatotoxicity (time to onset)2 days - 6 months
Hepatotoxicity (time to onset)1 day - 10 days
Hepatotoxicity (time to onset)
Hepatotoxicity (time to onset)1 day - 1.8 years
Hepatotoxicity (time to onset)1 week - 1 year
Hepatotoxicity (time to onset)6 months - 5 years
Hepatotoxicity (time to onset)3 days - 2.3 years
Hepatotoxicity (time to onset)2 days
Hepatotoxicity (time to onset)2 days - 9 years
Hepatotoxicity (time to onset)5 days - 17 days
Hepatotoxicity (time to onset)1 week
Hepatotoxicity (time to onset)4 days - 15 years
Hepatotoxicity (time to onset)1 day - 11 years
Hepatotoxicity (time to onset)1 month - 3 months
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3137740
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeActivity Comment
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)Allergic
Hepatotoxicity (mechanism)Allergic, Reactive metabolite
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)Allergic, Dose-dependant
Hepatotoxicity (mechanism)Allergic
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)Dose-dependant, Reactive metabolite
Hepatotoxicity (mechanism)Allergic, Reactive metabolite
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)Mitochondrial toxicity
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)Allergic
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)
Hepatotoxicity (mechanism)Allergic, Reactive metabolite
Hepatotoxicity (mechanism)
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Homo sapiens
External ID: CHEMBL4029349
Protocol: N/A
Comment: Journal: Drug Discov Today
Year: 2016
Volume: 21
Issue: 4
First Page: 648
Last Page: 653
DOI: 10.1016/j.drudis.2016.02.015

Target ChEMBL ID: CHEMBL372
ChEMBL Target Name: Homo sapiens
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard Value
DILI_severity_class=3
DILI_severity_class=3
DILI_severity_class=3
DILI_severity_class=8
DILI_severity_class=7
DILI_severity_class=3
DILI_severity_class=0
DILI_severity_class=0
DILI_severity_class=3
DILI_severity_class=5
DILI_severity_class=0
DILI_severity_class=8
DILI_severity_class=8
DILI_severity_class=4
DILI_severity_class=5
DILI_severity_class=0
DILI_severity_class=8
DILI_severity_class=8
DILI_severity_class=5
DILI_severity_class=8
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Homo sapiens
External ID: CHEMBL4029350
Protocol: N/A
Comment: Journal: Drug Discov Today
Year: 2016
Volume: 21
Issue: 4
First Page: 648
Last Page: 653
DOI: 10.1016/j.drudis.2016.02.015

Target ChEMBL ID: CHEMBL372
ChEMBL Target Name: Homo sapiens
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeActivity Comment
DILI_ConcernAmbiguous-Dili-Concern
DILI_ConcernLess-Dili-Concern
DILI_ConcernAmbiguous-Dili-Concern
DILI_ConcernMost-Dili-Concern
DILI_ConcernMost-Dili-Concern
DILI_ConcernLess-Dili-Concern
DILI_ConcernLess-Dili-Concern
DILI_ConcernNo-Dili-Concern
DILI_ConcernLess-Dili-Concern
DILI_ConcernAmbiguous-Dili-Concern
DILI_ConcernNo-Dili-Concern
DILI_ConcernMost-Dili-Concern
DILI_ConcernMost-Dili-Concern
DILI_ConcernAmbiguous-Dili-Concern
DILI_ConcernLess-Dili-Concern
DILI_ConcernNo-Dili-Concern
DILI_ConcernMost-Dili-Concern
DILI_ConcernLess-Dili-Concern
DILI_ConcernLess-Dili-Concern
DILI_ConcernMost-Dili-Concern
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Whole blood
External ID: CHEMBL3062764
Protocol: N/A
Comment: Journal: Med Chem Res
Year: 2012
Volume: 21
Issue: 12
First Page: 4357
Last Page: 4368
DOI: 10.1007/s00044-012-9977-1

Target ChEMBL ID: CHEMBL2367389
ChEMBL Target Name: Whole blood
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Retention_time=3.61min
Retention_time=2.6min
Retention_time=5.48min
Retention_time=2.7min
Retention_time=4.88min
Retention_time=5.81min
Retention_time=5.79min
Retention_time=5.13min
Retention_time=6.56min
Retention_time=6.22min
Retention_time=5.63min
Retention_time=2.1min
Retention_time=2.21min
Retention_time=5.28min
Retention_time=4.95min
Retention_time=6.08min
Retention_time=5.1min
Retention_time=5.92min
Retention_time=4.94min
Retention_time=5.99min
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3137722
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (moderate)=0references out of a total of 1
Hepatotoxicity (moderate)=61references out of a total of 69
Hepatotoxicity (moderate)=2references out of a total of 5
Hepatotoxicity (moderate)=7references out of a total of 27
Hepatotoxicity (moderate)=13references out of a total of 13
Hepatotoxicity (moderate)=1references out of a total of 1
Hepatotoxicity (moderate)=114references out of a total of 132
Hepatotoxicity (moderate)=15references out of a total of 23
Hepatotoxicity (moderate)=1references out of a total of 1
Hepatotoxicity (moderate)=3references out of a total of 9
Hepatotoxicity (moderate)=4references out of a total of 34
Hepatotoxicity (moderate)=1references out of a total of 5
Hepatotoxicity (moderate)=18references out of a total of 53
Hepatotoxicity (moderate)=1references out of a total of 1
Hepatotoxicity (moderate)=1references out of a total of 14
Hepatotoxicity (moderate)=3references out of a total of 5
Hepatotoxicity (moderate)=3references out of a total of 3
Hepatotoxicity (moderate)=3references out of a total of 16
Hepatotoxicity (moderate)=29references out of a total of 123
Hepatotoxicity (moderate)=1references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3137723
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Hepatotoxicity (moderate)=0%
Hepatotoxicity (moderate)=42.2%
Hepatotoxicity (moderate)=0%
Hepatotoxicity (moderate)=25%
Hepatotoxicity (moderate)=8.3%
Hepatotoxicity (moderate)=5%
Hepatotoxicity (moderate)=46.4%
Hepatotoxicity (moderate)=7.7%
Hepatotoxicity (moderate)=0%
Hepatotoxicity (moderate)=26%
Hepatotoxicity (moderate)=22%
Hepatotoxicity (moderate)=0%
Hepatotoxicity (moderate)=5.8%
Hepatotoxicity (moderate)=6%
Hepatotoxicity (moderate)=7.1%
Hepatotoxicity (moderate)=32%
Hepatotoxicity (moderate)=12.8%
Hepatotoxicity (moderate)=19%
Hepatotoxicity (moderate)=90%
Hepatotoxicity (moderate)=37%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137724
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (acute)=1references out of a total of 1
Hepatotoxicity (acute)=11references out of a total of 69
Hepatotoxicity (acute)=3references out of a total of 5
Hepatotoxicity (acute)=17references out of a total of 27
Hepatotoxicity (acute)=0references out of a total of 13
Hepatotoxicity (acute)=1references out of a total of 1
Hepatotoxicity (acute)=21references out of a total of 132
Hepatotoxicity (acute)=9references out of a total of 23
Hepatotoxicity (acute)=1references out of a total of 1
Hepatotoxicity (acute)=5references out of a total of 9
Hepatotoxicity (acute)=27references out of a total of 34
Hepatotoxicity (acute)=4references out of a total of 5
Hepatotoxicity (acute)=36references out of a total of 53
Hepatotoxicity (acute)=1references out of a total of 1
Hepatotoxicity (acute)=12references out of a total of 14
Hepatotoxicity (acute)=1references out of a total of 5
Hepatotoxicity (acute)=0references out of a total of 3
Hepatotoxicity (acute)=5references out of a total of 16
Hepatotoxicity (acute)=84references out of a total of 123
Hepatotoxicity (acute)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:NON-PROTEIN TARGET
External ID: CHEMBL3137725
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
Hepatotoxicity (acute)=0.2%
Hepatotoxicity (acute)=18.2%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=1%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=1.7%
Hepatotoxicity (acute)=0.2%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=2%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=5%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=0%
Hepatotoxicity (acute)=2%
Hepatotoxicity (acute)=0%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL3137726
Protocol: N/A
Comment: Journal: Gastroenterol Clin Biol
Year: 2004
Volume: 28
Issue: 8-9
First Page: 720
Last Page: 759
DOI: 10.1016/s0399-8320(04)95062-2
Standard TypeStandard RelationStandard ValueActivity Comment
Hepatotoxicity (cytolytic)=0references out of a total of 1
Hepatotoxicity (cytolytic)=6references out of a total of 69
Hepatotoxicity (cytolytic)=1references out of a total of 5
Hepatotoxicity (cytolytic)=8references out of a total of 27
Hepatotoxicity (cytolytic)=0references out of a total of 13
Hepatotoxicity (cytolytic)=1references out of a total of 1
Hepatotoxicity (cytolytic)=7references out of a total of 132
Hepatotoxicity (cytolytic)=3references out of a total of 23
Hepatotoxicity (cytolytic)=0references out of a total of 1
Hepatotoxicity (cytolytic)=3references out of a total of 9
Hepatotoxicity (cytolytic)=9references out of a total of 34
Hepatotoxicity (cytolytic)=3references out of a total of 5
Hepatotoxicity (cytolytic)=27references out of a total of 53
Hepatotoxicity (cytolytic)=1references out of a total of 1
Hepatotoxicity (cytolytic)=3references out of a total of 14
Hepatotoxicity (cytolytic)=1references out of a total of 5
Hepatotoxicity (cytolytic)=0references out of a total of 3
Hepatotoxicity (cytolytic)=0references out of a total of 16
Hepatotoxicity (cytolytic)=53references out of a total of 123
Hepatotoxicity (cytolytic)=0references out of a total of 4
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Hepatotoxicity
External ID: CHEMBL1697799
Protocol: N/A
Comment: Journal: Curr Drug Discov Technol
Year: 2004
Volume: 1
Issue: 4
First Page: 243
Last Page: 254
DOI: 10.2174/1570163043334794

Target ChEMBL ID: CHEMBL1697861
ChEMBL Target Name: Hepatotoxicity
ChEMBL Target Type: PHENOTYPE - Target is a biological phenotype or process
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
SGOT Increase - Index ValueData Not Available
SGOT Increase - Number of ReportsData Not Available
SGOT Increase - Activity ScoreData Not Available
SGOT Increase - Activity ScoreInactive
SGOT Increase - Index Value=0.6
SGOT Increase - Number of Reports<4
SGOT Increase - Activity ScoreInactive
SGOT Increase - Index Value=1.9
SGOT Increase - Number of Reports>=4
SGOT Increase - Activity ScoreMarginally Active
SGOT Increase - Index Value=3.8
SGOT Increase - Number of Reports>=4
SGOT Increase - Activity ScoreMarginally Active
SGOT Increase - Index Value=3.1
SGOT Increase - Number of Reports>=4
SGOT Increase - Activity ScoreActive
SGOT Increase - Number of Reports>=4
SGOT Increase - Index Value=5.6
SGOT Increase - Activity ScoreInactive
SGOT Increase - Index Value=1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Hepatotoxicity
External ID: CHEMBL1697800
Protocol: N/A
Comment: Journal: Curr Drug Discov Technol
Year: 2004
Volume: 1
Issue: 4
First Page: 243
Last Page: 254
DOI: 10.2174/1570163043334794

Target ChEMBL ID: CHEMBL1697861
ChEMBL Target Name: Hepatotoxicity
ChEMBL Target Type: PHENOTYPE - Target is a biological phenotype or process
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
SGPT Increase - Index ValueData Not Available
SGPT Increase - Number of ReportsData Not Available
SGPT Increase - Activity ScoreData Not Available
SGPT Increase - Activity ScoreInactive
SGPT Increase - Index Value=0.6
SGPT Increase - Number of Reports<4
SGPT Increase - Activity ScoreInactive
SGPT Increase - Index Value=2.1
SGPT Increase - Number of Reports>=4
SGPT Increase - Index ValueData Not Available
SGPT Increase - Number of ReportsData Not Available
SGPT Increase - Activity ScoreData Not Available
SGPT Increase - Activity ScoreInactive
SGPT Increase - Index Value=2.1
SGPT Increase - Number of Reports>=4
SGPT Increase - Activity ScoreMarginally Active
SGPT Increase - Index Value=3
SGPT Increase - Number of Reports>=4
SGPT Increase - Activity ScoreInactive
SGPT Increase - Index Value=0.5
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Hepatotoxicity
External ID: CHEMBL1697801
Protocol: N/A
Comment: Journal: Curr Drug Discov Technol
Year: 2004
Volume: 1
Issue: 4
First Page: 243
Last Page: 254
DOI: 10.2174/1570163043334794

Target ChEMBL ID: CHEMBL1697861
ChEMBL Target Name: Hepatotoxicity
ChEMBL Target Type: PHENOTYPE - Target is a biological phenotype or process
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
LDH Increase - Index ValueData Not Available
LDH Increase - Number of ReportsData Not Available
LDH Increase - Activity ScoreData Not Available
LDH Increase - Activity ScoreInactive
LDH Increase - Index Value=0.9
LDH Increase - Number of Reports<4
LDH Increase - Activity ScoreInactive
LDH Increase - Index Value=1.2
LDH Increase - Number of Reports>=4
LDH Increase - Index ValueData Not Available
LDH Increase - Number of ReportsData Not Available
LDH Increase - Activity ScoreData Not Available
LDH Increase - Activity ScoreInactive
LDH Increase - Index Value=0.9
LDH Increase - Number of Reports>=4
LDH Increase - Activity ScoreMarginally Active
LDH Increase - Index Value=3.7
LDH Increase - Number of Reports>=4
LDH Increase - Activity ScoreInactive
LDH Increase - Index Value=0.5
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Hepatotoxicity
External ID: CHEMBL1697802
Protocol: N/A
Comment: Journal: Curr Drug Discov Technol
Year: 2004
Volume: 1
Issue: 4
First Page: 243
Last Page: 254
DOI: 10.2174/1570163043334794

Target ChEMBL ID: CHEMBL1697861
ChEMBL Target Name: Hepatotoxicity
ChEMBL Target Type: PHENOTYPE - Target is a biological phenotype or process
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
GGT Increase - Index ValueData Not Available
GGT Increase - Number of ReportsData Not Available
GGT Increase - Activity ScoreData Not Available
GGT Increase - Activity ScoreInactive
GGT Increase - Index Value=0.3
GGT Increase - Number of Reports<4
GGT Increase - Activity ScoreInactive
GGT Increase - Index Value=0.5
GGT Increase - Number of Reports<4
GGT Increase - Index ValueData Not Available
GGT Increase - Number of ReportsData Not Available
GGT Increase - Activity ScoreData Not Available
GGT Increase - Activity ScoreInactive
GGT Increase - Index Value=0.8
GGT Increase - Number of Reports>=4
GGT Increase - Activity ScoreInactive
GGT Increase - Index Value=0
GGT Increase - Number of Reports<4
GGT Increase - Activity ScoreInactive
GGT Increase - Index Value=0
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Hepatotoxicity
External ID: CHEMBL1697797
Protocol: N/A
Comment: Journal: Curr Drug Discov Technol
Year: 2004
Volume: 1
Issue: 4
First Page: 243
Last Page: 254
DOI: 10.2174/1570163043334794

Target ChEMBL ID: CHEMBL1697861
ChEMBL Target Name: Hepatotoxicity
ChEMBL Target Type: PHENOTYPE - Target is a biological phenotype or process
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
Composite Activity - Marginal=0
Composite Activity - ScoreActive
Composite Activity - Marginal=1
Composite Activity - Active=4
Composite Activity - ScoreActive
Composite Activity - Marginal=0
Composite Activity - Active=4
Composite Activity - ScoreData Not Available
Composite Activity - Active=1
Composite Activity - Marginal=1
Composite Activity - ScoreActive
Composite Activity - Marginal=1
Composite Activity - Active=3
Composite Activity - ScoreInactive
Composite Activity - Active=1
Composite Activity - Marginal=2
Composite Activity - ScoreInactive
Composite Activity - Active=0
Composite Activity - Marginal=0
Composite Activity - ScoreActive
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Hepatotoxicity
External ID: CHEMBL1697798
Protocol: N/A
Comment: Journal: Curr Drug Discov Technol
Year: 2004
Volume: 1
Issue: 4
First Page: 243
Last Page: 254
DOI: 10.2174/1570163043334794

Target ChEMBL ID: CHEMBL1697861
ChEMBL Target Name: Hepatotoxicity
ChEMBL Target Type: PHENOTYPE - Target is a biological phenotype or process
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueActivity Comment
Alkaline Phosphatase Increase - Index ValueData Not Available
Alkaline Phosphatase Increase - Number of ReportsData Not Available
Alkaline Phosphatase Increase - Activity ScoreData Not Available
Alkaline Phosphatase Increase - Activity ScoreInactive
Alkaline Phosphatase Increase - Index Value=0
Alkaline Phosphatase Increase - Number of Reports<4
Alkaline Phosphatase Increase - Activity ScoreInactive
Alkaline Phosphatase Increase - Index Value=1.2
Alkaline Phosphatase Increase - Number of Reports>=4
Alkaline Phosphatase Increase - Activity ScoreMarginally Active
Alkaline Phosphatase Increase - Index Value=3.1
Alkaline Phosphatase Increase - Number of Reports>=4
Alkaline Phosphatase Increase - Activity ScoreInactive
Alkaline Phosphatase Increase - Index Value=2.3
Alkaline Phosphatase Increase - Number of Reports>=4
Alkaline Phosphatase Increase - Activity ScoreActive
Alkaline Phosphatase Increase - Number of Reports>=4
Alkaline Phosphatase Increase - Index Value=6.3
Alkaline Phosphatase Increase - Activity ScoreInactive
Alkaline Phosphatase Increase - Index Value=0.5