HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Vibrio anguillarum

External ID: CHEMBL993872

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2003
Volume: 66
Issue: 10
First Page: 1299
Last Page: 1301
DOI: 10.1021/np030233e

Target ChEMBL ID: CHEMBL612298
ChEMBL Target Name: Vibrio anguillarum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
MIC	=	0.05	ug.mL-1
MIC	=	0.04	ug.mL-1
MIC	=	0.11	ug.mL-1
MIC	=	0.13	ug.mL-1
MIC	=	0.13	ug.mL-1
MIC	=	0.14	ug.mL-1
MIC	=	0.12	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bacillus subtilis

External ID: CHEMBL5121453

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL359
ChEMBL Target Name: Bacillus subtilis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA
MIC	=	2.1	ug.mL-1
MIC	=	66.7	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Candida albicans

External ID: CHEMBL5121454

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL366
ChEMBL Target Name: Candida albicans
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NCI-H460

External ID: CHEMBL4036567

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2017
Volume: 27
Issue: 15
First Page: 3595
Last Page: 3601
DOI: 10.1016/j.bmcl.2017.03.095

Target ChEMBL ID: CHEMBL396
ChEMBL Target Name: NCI-H460
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
4.56	IC50	=	4560	nM
50	IC50	>	50000	nM
50	IC50	>	50000	nM
50	IC50	>	50000	nM
50	IC50	>	50000	nM
5.66	IC50	=	5660	nM
50	IC50	>	50000	nM
23.12	IC50	=	23120	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL3788047

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	40	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL3788044

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HUVEC

External ID: CHEMBL3788048

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL613979
ChEMBL Target Name: HUVEC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active
Activity	Not Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL3792269

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Active
Inhibition	%	Active
Inhibition	%	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Schizosaccharomyces pombe

External ID: CHEMBL5121463

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL612632
ChEMBL Target Name: Schizosaccharomyces pombe
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HUVEC

External ID: CHEMBL3792268

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL613979
ChEMBL Target Name: HUVEC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Dose-dependent effect
Inhibition	%	Dose-dependent effect
Inhibition	%	Dose-dependent effect

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Staphylococcus aureus

External ID: CHEMBL5121464

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL352
ChEMBL Target Name: Staphylococcus aureus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA
MIC	=	1.04	ug.mL-1
MIC	=	66.7	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HUVEC

External ID: CHEMBL3792267

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL613979
ChEMBL Target Name: HUVEC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Units	Activity Comment
Inhibition	%	Active
Inhibition	%	Active
Inhibition	%	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：L929

External ID: CHEMBL5121465

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL612267
ChEMBL Target Name: L929
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
66	IC50	=	66000	nM
18	IC50	=	18000	nM
50	IC50	=	50000	nM
	IC50				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：KB 3-1

External ID: CHEMBL5121466

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL614590
ChEMBL Target Name: KB 3-1
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
62.5	IC50	=	62500	nM
7.7	IC50	=	7700	nM
10.2	IC50	=	10200	nM
	IC50				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HUVEC

External ID: CHEMBL3788039

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL613979
ChEMBL Target Name: HUVEC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Dose-dependent effect
Activity	Dose-dependent effect
Activity	Dose-dependent effect

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycolicibacterium smegmatis

External ID: CHEMBL5121459

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL613088
ChEMBL Target Name: Mycolicibacterium smegmatis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC	=	1.7	ug.mL-1
MIC				NA
MIC				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HUVEC

External ID: CHEMBL3788038

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL613979
ChEMBL Target Name: HUVEC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Wickerhamomyces anomalus

External ID: CHEMBL5121460

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL613004
ChEMBL Target Name: Wickerhamomyces anomalus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HUVEC

External ID: CHEMBL3788037

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL613979
ChEMBL Target Name: HUVEC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Dose-dependent effect
Activity	Dose-dependent effect
Activity	Dose-dependent effect

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Pseudomonas aeruginosa

External ID: CHEMBL5121461

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL348
ChEMBL Target Name: Pseudomonas aeruginosa
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA
MIC	=	0.4	ug.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HUVEC

External ID: CHEMBL3788036

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL613979
ChEMBL Target Name: HUVEC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Rhodotorula glutinis

External ID: CHEMBL5121462

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL613275
ChEMBL Target Name: Rhodotorula glutinis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Chromobacterium violaceum

External ID: CHEMBL5121455

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL613862
ChEMBL Target Name: Chromobacterium violaceum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Escherichia coli

External ID: CHEMBL5121456

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL354
ChEMBL Target Name: Escherichia coli
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL3788041

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Micrococcus luteus

External ID: CHEMBL5121457

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL614421
ChEMBL Target Name: Micrococcus luteus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HUVEC

External ID: CHEMBL3788040

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2016
Volume: 26
Issue: 8
First Page: 1873
Last Page: 1876
DOI: 10.1016/j.bmcl.2016.03.030

Target ChEMBL ID: CHEMBL613979
ChEMBL Target Name: HUVEC
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-toxic
Activity	Non-toxic
Activity	Non-toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mucor hiemalis

External ID: CHEMBL5121458

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 2022
Volume: 85
Issue: 4.0
First Page: 846
Last Page: 856
DOI: 10.1021/acs.jnatprod.1c00975

Target ChEMBL ID: CHEMBL612949
ChEMBL Target Name: Mucor hiemalis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
MIC				NA
MIC				NA
MIC	=	33.33	ug.mL-1

36238-67-2 靶点实验数据