HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL999157

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1998
Volume: 61
Issue: 7
First Page: 896
Last Page: 900
DOI: 10.1021/np980028c

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	5.95	ug ml-1
ED50	=	4.95	ug ml-1
ED50	=	7.64	ug ml-1
ED50	=	10.44	ug ml-1
ED50	=	63.54	ug ml-1
ED50	=	59.32	ug ml-1
ED50	=	58.09	ug ml-1
ED50	=	95.92	ug ml-1
ED50	=	70.98	ug ml-1
ED50	=	39.86	ug ml-1
ED50	=	0.015	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HT-1080

External ID: CHEMBL999156

Protocol: N/A

Comment: Journal: J Nat Prod
Year: 1998
Volume: 61
Issue: 7
First Page: 896
Last Page: 900
DOI: 10.1021/np980028c

Target ChEMBL ID: CHEMBL614580
ChEMBL Target Name: HT-1080
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
ED50	=	2.91	ug ml-1
ED50	=	5.83	ug ml-1
ED50	=	2.3	ug ml-1
ED50	=	4.05	ug ml-1
ED50	=	72.91	ug ml-1
ED50	=	45.47	ug ml-1
ED50	=	57.4	ug ml-1
ED50	=	75.43	ug ml-1
ED50	=	26.97	ug ml-1
ED50	=	38.92	ug ml-1
ED50	=	0.034	ug ml-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3635258

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2015
Volume: 23
Issue: 21
First Page: 6922
Last Page: 6929
DOI: 10.1016/j.bmc.2015.09.042

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	EC50	>	100000	nM
100	EC50	>	100000	nM
100	EC50	>	100000	nM
12.6	EC50	=	12600	nM
100	EC50	>	100000	nM
10	EC50	=	10000	nM
100	EC50	>	100000	nM
100	EC50	>	100000	nM
100	EC50	>	100000	nM
24.5	EC50	=	24500	nM
100	EC50	>	100000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：RAW264.7

External ID: CHEMBL3635257

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2015
Volume: 23
Issue: 21
First Page: 6922
Last Page: 6929
DOI: 10.1016/j.bmc.2015.09.042

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Inhibition	<	10	%
Inhibition	<	10	%
Inhibition	<	10	%
Inhibition	<	10	%
Inhibition	<	10	%
Inhibition	<	10	%
Inhibition	<	10	%
Inhibition	=	72	%
Inhibition	=	40	%
Inhibition	=	70	%
Inhibition	<	10	%

3570-69-2 靶点实验数据