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34883-43-7 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Androgen receptor
External ID: CHEMBL872182
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 2005
Volume: 48
Issue: 18
First Page: 5666
Last Page: 5674
DOI: 10.1021/jm050403f

Target ChEMBL ID: CHEMBL3072
ChEMBL Target Name: Androgen Receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
64.5654IC50=64565.42nM
47.863IC50=47863.01nM
57.544IC50=57543.99nM
1.28825IC50=1288.25nM
54.9541IC50=54954.09nM
12.0226IC50=12022.64nM
42.6579IC50>42657.95nM
1.54882IC50=1548.82nM
426.58IC50>426579.52nMOutside typical range
37.1535IC50=37153.52nM
18.197IC50=18197.01nM
40.738IC50=40738.03nM
144.544IC50=144543.98nMOutside typical range
42.6579IC50>42657.95nM
77.6247IC50=77624.71nM
42.6579IC50>42657.95nM
0.40738IC50=407.38nM
8.12831IC50=8128.31nM
12.8825IC50=12882.5nM
0.79433IC50=794.33nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL1786463
Protocol: N/A
Comment: Journal: J. Med. Chem.
Year: 2011
Volume: 54
Issue: 6
First Page: 1539
Last Page: 1554
DOI: 10.1021/jm101356p
Standard TypeStandard RelationStandard ValueStandard Units
Solubility=400ug.mL-1
Solubility=637ug.mL-1
Solubility=1300ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL1798350
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2008
Volume: 43
Issue: 4
First Page: 714
Last Page: 740
DOI: 10.1016/j.ejmech.2007.05.007
Standard TypeStandard RelationStandard Value
LogP=0.83
LogP=6.169
LogP=4.03
LogP=6.882
LogP=2.14
LogP=4.95
LogP=3.868
LogP=3.354
LogP=3.005
LogP=2.855
LogP=1.994
LogP=2.285
LogP=0.842
LogP=2.481
LogP=4.225
LogP=3.316
LogP=6.036
LogP=2.791
LogP=2.142
LogP=2.81