HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_8977_2

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	IC50	Target Accession(s)	Ligand	Target
IC50	8.733	8733	Q7Z628	BDBM50337824	Neuroepithelial cell-transforming gene 1 protein
IC50	0.009	9	Q7Z628	BDBM50337830	Neuroepithelial cell-transforming gene 1 protein
IC50	0.019	19	Q7Z628	BDBM50337834	Neuroepithelial cell-transforming gene 1 protein
IC50	0.01	10	Q7Z628	BDBM50337836	Neuroepithelial cell-transforming gene 1 protein
IC50	0.061	61	Q7Z628	BDBM50337846	Neuroepithelial cell-transforming gene 1 protein
IC50	0.137	137	Q7Z628	BDBM50337849	Neuroepithelial cell-transforming gene 1 protein
IC50	0.146	146	Q7Z628	BDBM50337850	Neuroepithelial cell-transforming gene 1 protein
IC50	4.034	4034	Q7Z628	BDBM50337903	Neuroepithelial cell-transforming gene 1 protein
IC50	3.177	3177	Q7Z628	BDBM50337905	Neuroepithelial cell-transforming gene 1 protein
IC50	1.901	1901	Q7Z628	BDBM50337905	Neuroepithelial cell-transforming gene 1 protein
IC50	4.027	4027	Q7Z628	BDBM50337905	Neuroepithelial cell-transforming gene 1 protein
IC50	0.167	167	Q7Z628	BDBM50337909	Neuroepithelial cell-transforming gene 1 protein
IC50	0.036	36	Q7Z628	BDBM50337910	Neuroepithelial cell-transforming gene 1 protein
IC50	0.01	10	Q7Z628	BDBM50337910	Neuroepithelial cell-transforming gene 1 protein
IC50	0.57	570	Q7Z628	BDBM50337910	Neuroepithelial cell-transforming gene 1 protein
IC50	0.888	888	Q7Z628	BDBM50337915	Neuroepithelial cell-transforming gene 1 protein
IC50	0.964	964	Q7Z628	BDBM50337916	Neuroepithelial cell-transforming gene 1 protein
IC50	0.189	189	Q7Z628	BDBM433561	Neuroepithelial cell-transforming gene 1 protein
IC50	0.026	26	Q7Z628	BDBM433561	Neuroepithelial cell-transforming gene 1 protein
IC50	0.004	4	Q7Z628	BDBM433566	Neuroepithelial cell-transforming gene 1 protein

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_8977_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	IC50	Target Accession(s)	Ligand	Target
IC50	0.855	855	P31645	BDBM50337824	Sodium-dependent serotonin transporter
IC50	0.156	156	P31645	BDBM50337830	Sodium-dependent serotonin transporter
IC50	0.158	158	P31645	BDBM50337834	Sodium-dependent serotonin transporter
IC50	0.031	31	P31645	BDBM50337836	Sodium-dependent serotonin transporter
IC50	0.057	57	P31645	BDBM50337846	Sodium-dependent serotonin transporter
IC50	0.688	688	P31645	BDBM50337849	Sodium-dependent serotonin transporter
IC50	0.224	224	P31645	BDBM50337850	Sodium-dependent serotonin transporter
IC50	1.764	1764	P31645	BDBM50337903	Sodium-dependent serotonin transporter
IC50	0.107	107	P31645	BDBM50337905	Sodium-dependent serotonin transporter
IC50	1.514	1514	P31645	BDBM50337905	Sodium-dependent serotonin transporter
IC50	0.398	398	P31645	BDBM50337905	Sodium-dependent serotonin transporter
IC50	0.406	406	P31645	BDBM50337909	Sodium-dependent serotonin transporter
IC50	0.065	65	P31645	BDBM50337910	Sodium-dependent serotonin transporter
IC50	0.012	12	P31645	BDBM50337910	Sodium-dependent serotonin transporter
IC50	0.239	239	P31645	BDBM50337910	Sodium-dependent serotonin transporter
IC50	0.331	331	P31645	BDBM50337915	Sodium-dependent serotonin transporter
IC50	5.936	5936	P31645	BDBM50337916	Sodium-dependent serotonin transporter
IC50	1.03	1030	P31645	BDBM433561	Sodium-dependent serotonin transporter
IC50	0.673	673	P31645	BDBM433561	Sodium-dependent serotonin transporter
IC50	0.051	51	P31645	BDBM433566	Sodium-dependent serotonin transporter

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_8977_3

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	Standard Relation	PubChem Standard Value	IC50 Qualifier	IC50	Target Accession(s)	Ligand	Target
IC50		0.996		996	Q01959	BDBM50337824	Sodium-dependent dopamine transporter
IC50		0.001		1	Q01959	BDBM50337830	Sodium-dependent dopamine transporter
IC50		0.004		4	Q01959	BDBM50337834	Sodium-dependent dopamine transporter
IC50		0.011		11	Q01959	BDBM50337836	Sodium-dependent dopamine transporter
IC50		0.057		57	Q01959	BDBM50337846	Sodium-dependent dopamine transporter
IC50		0.17		170	Q01959	BDBM50337849	Sodium-dependent dopamine transporter
IC50		0.546		546	Q01959	BDBM50337850	Sodium-dependent dopamine transporter
IC50		4.085		4085	Q01959	BDBM50337903	Sodium-dependent dopamine transporter
IC50		2.316		2316	Q01959	BDBM50337905	Sodium-dependent dopamine transporter
IC50		0.696		696	Q01959	BDBM50337905	Sodium-dependent dopamine transporter
IC50		0.735		735	Q01959	BDBM50337905	Sodium-dependent dopamine transporter
IC50		0.18		180	Q01959	BDBM50337909	Sodium-dependent dopamine transporter
IC50		0.085		85	Q01959	BDBM50337910	Sodium-dependent dopamine transporter
IC50		0.036		36	Q01959	BDBM50337910	Sodium-dependent dopamine transporter
IC50		0.219		219	Q01959	BDBM50337910	Sodium-dependent dopamine transporter
IC50	<	0.001	<	1	Q01959	BDBM50337915	Sodium-dependent dopamine transporter
IC50		0.009		9	Q01959	BDBM50337916	Sodium-dependent dopamine transporter
IC50		1.19		1190	Q01959	BDBM433561	Sodium-dependent dopamine transporter
IC50		0.427		427	Q01959	BDBM433561	Sodium-dependent dopamine transporter
IC50		0.066		66	Q01959	BDBM433566	Sodium-dependent dopamine transporter

342425-45-0 靶点实验数据