HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Proline--tRNA ligase, cytoplasmic

External ID: CHEMBL844880

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2001
Volume: 11
Issue: 4
First Page: 541
Last Page: 544
DOI: 10.1016/s0960-894x(00)00697-1

Target ChEMBL ID: CHEMBL4636
ChEMBL Target Name: Prolyl-tRNA synthetase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.07	IC50	=	70	nM
100	IC50	>	100000	nM
1.5	IC50	=	1500	nM
0.14	IC50	=	140	nM
1.5	IC50	=	1500	nM
0.22	IC50	=	220	nM
100	IC50	>	100000	nM
1.3	IC50	=	1300	nM
3.3	IC50	=	3300	nM
0.026	IC50	=	26	nM
0.02	IC50	=	20	nM
8.8	IC50	=	8800	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Bifunctional glutamate/proline--tRNA ligase

External ID: CHEMBL844884

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 2001
Volume: 11
Issue: 4
First Page: 541
Last Page: 544
DOI: 10.1016/s0960-894x(00)00697-1

Target ChEMBL ID: CHEMBL3873
ChEMBL Target Name: Aminoacyl-tRNA synthetase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	IC50	>	100000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM
56	IC50	=	56000	nM
100	IC50	>	100000	nM
80	IC50	=	80000	nM
95	IC50	=	95000	nM
20	IC50	>	20000	nM
100	IC50	>	100000	nM
100	IC50	>	100000	nM

342017-95-2 靶点实验数据