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34152-86-8 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Beta-secretase 1
External ID: CHEMBL1169087
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2010
Volume: 18
Issue: 9
First Page: 3088
Last Page: 3115
DOI: 10.1016/j.bmc.2010.03.043

Target ChEMBL ID: CHEMBL4822
ChEMBL Target Name: Beta-secretase 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
0.046IC50=46nM
100IC50=100000nM
100IC50=100000nM
500IC50=500000nMOutside typical range
100IC50=100000nM
2.2IC50=2200nM
100IC50=100000nM
5IC50=5000nM
48.1IC50=48100nM