HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：Shanghai Institute of Organic Chemistry 靶标：N/A

External ID: PDBbind-Ki for protein-ligand complexes

Protocol:

Comment:

PDBbind Data Link	Affinity_Quilifier	Ki	PubMed	Protein Target	Protein Name	MMDB	PDB
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mto	=	0.11	12390023	1MTO_A,1MTO_B	6-phosphofructokinase	21480	1MTO
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mu6	=	0.0042	12570369	1MU6_B	thrombin alpha	26736	1MU6
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mue	=	0.0023	12657281	1MUE_B	thrombin alpha	26738	1MUE
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mx1	>	100	12725862	1MX1_A	carboxylesterase i	22651	1MX1
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1mxo	=	0.001		1MXO_A	beta-lactamase	22061	1MXO
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1my8	=	0.035		1MY8_A	beta-lactamase	22064	1MY8
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n1v	=	140	12507479	1N1V_A	neuraminidase (sialidase)	21810	1N1V
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n2v	=	83	12646024	1N2V_A	queuine tRNA-ribosyltransferase	22661	1N2V
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n3i	=	0.0013	12755607	1N3I_A,1N3I_B	purine nucleoside phosphorylase	24646	1N3I
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n46	=	3.0E-5	12565933	1N46_A	thyroid hormone receptor beta-1	22662	1N46
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n4h	=	0.28	12958591	1N4H_A	nuclear receptor ror-beta	24647	1N4H
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n5r	=	2.2	12505979	1N5R_A	acetylcholinesterase	21834	1N5R
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1n7i	=	0.26	14695818	1N7I_A	phenylethanolamine n-methyltransferase	25597	1N7I
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nc1	=	0.75	12496243	1NC1_A,1NC1_B	mta/sah nucleosidase	25250	1NC1
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nc3	=	10	12496243	1NC3_A,1NC3_B	mta/sah nucleosidase	22390	1NC3
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nde	=	0.015	12459017	1NDE_A	estrogen receptor beta	21544	1NDE
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ndz	=	0.0077	14709046	1NDZ_A	adenosine deaminase	25613	1NDZ
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nhv	=	2.2	12509436	1NHV_A	rna-dependent rna polymerase	22403	1NHV
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1nny	=	0.022	12670229	1NNY_A	tyrosine phosphatase 1b	22696	1NNY
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1noj	=	700	8652510	1NOJ_A	glycogen phosphorylase	56992	1NOJ

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：Shanghai Institute of Organic Chemistry 靶标：N/A

External ID: PDBbind-Kd for protein-ligand complexes

Protocol:

Comment:

PDBbind Data Link	Affinity_Quilifier	Kd	PubMed	Protein Target	Protein Name	MMDB	PDB
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1a1e	=	1	9174343	1A1E_B	tyrosine kinase C-src	73432	1A1E
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1a7c	<=	100	9634700	1A7C_A	plasminogen activator inhibitor type 1	97714	1A7C
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1adl	=	4.4	7929228	1ADL_A	trp rna-binding attenuation protein	55147	1ADL
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ado	=	1	8989320	1ADO_A	fructose 1,6-bisphosphate aldolase	6825	1ADO
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1af6	=	15000	9299337	1AF6_A,1AF6_B	maltoporin	7612	1AF6
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ag9	=	0.001	9416602	1AG9_A	flavodoxin	6827	1AG9
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ahx	=	120	7664122	1AHX_A,1AHX_B	aspartate aminotransferase	3769	1AHX
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ahy	=	440	7664122	1AHY_A,1AHY_B	aspartate aminotransferase	3768	1AHY
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1aj6	=	1.2	9245398	1AJ6_A	DNA gyrase b	55222	1AJ6
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1aj7	=	135	9180069	1AJ7_L,1AJ7_H	immunoglobulin 48g7 germline fab	6588	1AJ7
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akq	=	7.9E-4	9874201	1AKQ_A	flavodoxin	55243	1AKQ
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akr	=	8.2E-4	9622492	1AKR_A	flavodoxin	55244	1AKR
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akt	=	0.0032	9622492	1AKT_A	flavodoxin	55245	1AKT
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1aku	=	0.746		1AKU_A	flavodoxin	55246	1AKU
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akv	=	2.6E-6		1AKV_A	flavodoxin	55247	1AKV
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1akw	=	0.0026	9622492	1AKW_A	flavodoxin	55248	1AKW
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1amw	=	29	9230303	1AMW_A	heat shock protein 90	55278	1AMW
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1ao0	=	11	9271502	1AO0_A,1AO0_B	glutamine phosphoribosylpyrophosphate	6600	1AO0
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1apb	=	1.51	2204627	1APB_A	apolipoprotein	55308	1APB
http://www.pdbbind.org.cn/quickpdb.asp?quickpdb=1aqi	=	2.4	8995524	1AQI_A	adenine-n6-dna-methyltransferase taqi	5182	1AQI

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：BindingDB 靶标：N/A

External ID: BindingDB_2689_1

Protocol: N/A

Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.

Standard Type	PubChem Standard Value	Kd	Target Accession(s)	Ligand	Target
Kd	35	35000	O67648	BDBM23437	UDP-3-O-acyl-N-acetylglucosamine deacetylase
Kd	6.2	6200	O67648	BDBM23438	UDP-3-O-acyl-N-acetylglucosamine deacetylase
Kd	2.3	2300	O67648	BDBM23439	UDP-3-O-acyl-N-acetylglucosamine deacetylase

3398-75-2 靶点实验数据