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33857-28-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Aryl hydrocarbon receptor
External ID: CHEMBL649365
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1997
Volume: 40
Issue: 26
First Page: 4360
Last Page: 4371
DOI: 10.1021/jm970488n

Target ChEMBL ID: CHEMBL3201
ChEMBL Target Name: Aryl hydrocarbon receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
0.01EC50=10nM
0.19999EC50=199.99nM
0.34995EC50=349.95nM
0.44978EC50=449.78nM
1EC50=1000nM
0.001479EC50=1.479nM
279.898EC50=279898.13nMOutside typical range
0.29512EC50=295.12nM
1.09901EC50=1099.01nM
99.0832EC50=99083.19nM
3.1989EC50=3198.9nM
0.07096EC50=70.96nM
5.00035EC50=5000.35nM
15.9956EC50=15995.58nM
1.30017EC50=1300.17nM
7.09578EC50=7095.78nM
0.79433EC50=794.33nM
0.2799EC50=279.9nM
0.21979EC50=219.79nM
0.15996EC50=159.96nM