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3306-29-4 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:N/A
External ID: CHEMBL2209569
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2069
Last Page: 2075
DOI: 10.1021/np3003673
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
0.71IC50=710nM
116.82IC50=116820nMOutside typical range
65.34IC50=65340nM
85.34IC50=85340nM
156.54IC50=156540nMOutside typical range
102.56IC50=102560nMOutside typical range
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:RAW264.7
External ID: CHEMBL2209570
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2069
Last Page: 2075
DOI: 10.1021/np3003673

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
IC50Not Determined
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:RAW264.7
External ID: CHEMBL2209567
Protocol: N/A
Comment: Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2069
Last Page: 2075
DOI: 10.1021/np3003673

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeActivity Comment
ActivityNon-toxic
ActivityNon-toxic
ActivityNon-toxic
ActivityNon-toxic
ActivityNon-toxic
ActivityNon-toxic
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:RAW264.7
External ID: CHEMBL2209568
Protocol: N/A
Comment: Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2069
Last Page: 2075
DOI: 10.1021/np3003673

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeActivity Comment
ActivityNon-toxic
ActivityNon-toxic
ActivityNon-toxic
ActivityNon-toxic
ActivityNon-toxic
ActivityNon-toxic
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:RAW264.7
External ID: CHEMBL2209571
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Nat. Prod.
Year: 2012
Volume: 75
Issue: 12
First Page: 2069
Last Page: 2075
DOI: 10.1021/np3003673

Target ChEMBL ID: CHEMBL612557
ChEMBL Target Name: RAW264.7
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
50IC50>50000nM
50IC50>50000nM
42.4IC50=42400nM
35IC50=35000nM
50IC50>50000nM
50IC50>50000nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Thrombin
External ID: CHEMBL2045782
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 54
First Page: 210
Last Page: 222
DOI: 10.1016/j.ejmech.2012.04.044

Target ChEMBL ID: CHEMBL2040703
ChEMBL Target Name: Thrombin
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
APTT=30.3s
APTT=40.3s
APTT=46.2s
APTT=42.4s
APTT=72.6s
APTT=61.7s
APTT=50.2s
APTT=54.7s
APTT=82.3s
APTT=49.8s
APTT=49.2s
APTT=52.2s
APTT=67.6s
APTT=57.6s
APTT=63.7s
APTT=49.3s
APTT=58.7s
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasma
External ID: CHEMBL5127306
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 228
First Page: 114035
Last Page: 114035
DOI: 10.1016/j.ejmech.2021.114035

Target ChEMBL ID: CHEMBL613450
ChEMBL Target Name: Plasma
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
TIME=0.001889hr
TIME=0.002111hr
TIME=0.001917hr
TIME=0.001611hr
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Thrombin
External ID: CHEMBL2045783
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 54
First Page: 210
Last Page: 222
DOI: 10.1016/j.ejmech.2012.04.044

Target ChEMBL ID: CHEMBL2040703
ChEMBL Target Name: Thrombin
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Activity=5.8g/L
Activity=8.9g/L
Activity=5.9g/L
Activity=8.4g/L
Activity=5.4g/L
Activity=5.3g/L
Activity=4.7g/L
Activity=7.3g/L
Activity=5.4g/L
Activity=7.5g/L
Activity=5g/L
Activity=6.7g/L
Activity=5.1g/L
Activity=6.2g/L
Activity=5.4g/L
Activity=7.9g/L
Activity=6.6g/L
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasma
External ID: CHEMBL5127307
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 228
First Page: 114035
Last Page: 114035
DOI: 10.1016/j.ejmech.2021.114035

Target ChEMBL ID: CHEMBL613450
ChEMBL Target Name: Plasma
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
TIME=0.02017hr
TIME=0.002778hr
TIME=0.01367hr
TIME=0.01878hr
TIME=0.01631hr
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Thrombin
External ID: CHEMBL2045780
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 54
First Page: 210
Last Page: 222
DOI: 10.1016/j.ejmech.2012.04.044

Target ChEMBL ID: CHEMBL2040703
ChEMBL Target Name: Thrombin
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
TT=19.2s
TT=11.6s
TT=14.8s
TT=14.2s
TT=23s
TT=14.9s
TT=22.9s
TT=22.5s
TT=20.5s
TT=16.6s
TT=19.4s
TT=13.4s
TT=21.8s
TT=22.3s
TT=20s
TT=15.9s
TT=9.9s
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Thrombin
External ID: CHEMBL2045781
Protocol: N/A
Comment: Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 54
First Page: 210
Last Page: 222
DOI: 10.1016/j.ejmech.2012.04.044

Target ChEMBL ID: CHEMBL2040703
ChEMBL Target Name: Thrombin
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
PT=6.2s
PT=5.2s
PT=7.4s
PT=5.4s
PT=6.8s
PT=6s
PT=4.8s
PT=7.3s
PT=5.3s
PT=6.9s
PT=7.6s
PT=5.8s
PT=6.9s
PT=5.8s
PT=5.7s
PT=5.1s
PT=5.8s
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Plasma
External ID: CHEMBL5127305
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 228
First Page: 114035
Last Page: 114035
DOI: 10.1016/j.ejmech.2021.114035

Target ChEMBL ID: CHEMBL613450
ChEMBL Target Name: Plasma
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
TIME=0.006389hr
TIME=0.002214hr
TIME=0.005389hr
TIME=0.006056hr
TIME=0.00275hr