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330-94-9 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Indoleamine 2,3-dioxygenase 1
External ID: CHEMBL3294616
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2014
Volume: 82
First Page: 96
Last Page: 105
DOI: 10.1016/j.ejmech.2014.05.044

Target ChEMBL ID: CHEMBL4685
ChEMBL Target Name: Indoleamine 2,3-dioxygenase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
15IC50=15000nM
50IC50>50000nM
50IC50>50000nM
50IC50>50000nM
2.7IC50=2700nM
3.7IC50=3700nM
3.8IC50=3800nM
1.8IC50=1800nM
3.5IC50=3500nM
1.2IC50=1200nM
50IC50>50000nM
34IC50=34000nM
18IC50=18000nM
50IC50>50000nM
50IC50>50000nM
17IC50=17000nM
50IC50>50000nM
34IC50=34000nM
50IC50>50000nM
50IC50>50000nM