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32367-75-2 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL3993276
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2017
Volume: 127
First Page: 147
Last Page: 158
DOI: 10.1016/j.ejmech.2016.12.042

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC90=0.03ug.mL-1
MIC90=10ug.mL-1
MIC90=100ug.mL-1
MIC90=0.3ug.mL-1
MIC90=19ug.mL-1
MIC90=60ug.mL-1
MIC90>64ug.mL-1
MIC90=100ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL3993275
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2017
Volume: 127
First Page: 147
Last Page: 158
DOI: 10.1016/j.ejmech.2016.12.042

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC=0.125ug.mL-1
MIC=8ug.mL-1
MIC=27ug.mL-1
MIC=0.25ug.mL-1
MIC=8ug.mL-1
MIC=64ug.mL-1
MIC=16ug.mL-1
MIC=8ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL3993278
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2017
Volume: 127
First Page: 147
Last Page: 158
DOI: 10.1016/j.ejmech.2016.12.042

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC90>25ug.mL-1
MIC90=11ug.mL-1
MIC90>100ug.mL-1
MIC90>25ug.mL-1
MIC90=16ug.mL-1
MIC90=48ug.mL-1
MIC90>64ug.mL-1
MIC90>100ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL3993277
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2017
Volume: 127
First Page: 147
Last Page: 158
DOI: 10.1016/j.ejmech.2016.12.042

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC90=0.03ug.mL-1
MIC90=8ug.mL-1
MIC90>100ug.mL-1
MIC90=8ug.mL-1
MIC90=16ug.mL-1
MIC90=39ug.mL-1
MIC90=47ug.mL-1
MIC90>100ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis variant bovis
External ID: CHEMBL3993274
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2017
Volume: 127
First Page: 147
Last Page: 158
DOI: 10.1016/j.ejmech.2016.12.042

Target ChEMBL ID: CHEMBL613086
ChEMBL Target Name: Mycobacterium tuberculosis variant bovis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC=0.063ug.mL-1
MIC=16ug.mL-1
MIC=64ug.mL-1
MIC=8ug.mL-1
MIC>64ug.mL-1
MIC=64ug.mL-1
MIC=8ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycolicibacterium smegmatis
External ID: CHEMBL3993273
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2017
Volume: 127
First Page: 147
Last Page: 158
DOI: 10.1016/j.ejmech.2016.12.042

Target ChEMBL ID: CHEMBL613088
ChEMBL Target Name: Mycolicibacterium smegmatis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC=4ug.mL-1
MIC=16ug.mL-1
MIC=64ug.mL-1
MIC=16ug.mL-1
MIC>64ug.mL-1
MIC=32ug.mL-1
MIC=16ug.mL-1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:BindingDB 靶标:N/A
External ID: BindingDB_8583_1
Protocol: N/A
Comment: Compounds with any of Ki, IC50, Kd, or EC50 activity value <= 10uM are labeled as "Active".
If multiple measurements are available for a given compound, it is labeled as "Active" if any of the measurements meet the criterion. Activity values are checked in the order of Ki, IC50, Kd, and EC50. The first entry that meets the above activity threshold is used to determine "Standard Type", "Standard Relation", and "PubChem Standard Value". Otherwise, the first non-empty entry will be used to set those values.
Standard TypePubChem Standard ValueIC50Target Accession(s)LigandTarget
IC506.256250P09211,Q9UDY8BDBM81470Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC5044000P09211,Q9UDY8BDBM50408503Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC505.85800P09211,Q9UDY8BDBM67545Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC500.85850P09211,Q9UDY8BDBM260159Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC5019.319300P09211,Q9UDY8BDBM260160Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC505.75700P09211,Q9UDY8BDBM260162Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC502.672670P09211,Q9UDY8BDBM260164Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC5011.511500P09211,Q9UDY8BDBM260167Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC5017.517500P09211,Q9UDY8BDBM260168Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC506.6976697P09211,Q9UDY8BDBM260174Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC509.699690P09211,Q9UDY8BDBM260175Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC505.755750P09211,Q9UDY8BDBM260176Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC5013.513500P09211,Q9UDY8BDBM260179Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC5015.915900P09211,Q9UDY8BDBM260182Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC5088000P09211,Q9UDY8BDBM260184Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC5021.321300P09211,Q9UDY8BDBM260186Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC501.851850P09211,Q9UDY8BDBM260191Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC501.8541854P09211,Q9UDY8BDBM260191Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
IC503.8633863P09211,Q9UDY8BDBM260196Glutathione S-transferase P/Mucosa-associated lymphoid tissue lymphoma translocation protein 1
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Mycobacterium tuberculosis
External ID: CHEMBL3993279
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2017
Volume: 127
First Page: 147
Last Page: 158
DOI: 10.1016/j.ejmech.2016.12.042

Target ChEMBL ID: CHEMBL360
ChEMBL Target Name: Mycobacterium tuberculosis
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular
Standard TypeStandard RelationStandard ValueStandard Units
MIC90>25ug.mL-1
MIC90=10ug.mL-1
MIC90>100ug.mL-1
MIC90>25ug.mL-1
MIC90=12ug.mL-1
MIC90=46ug.mL-1
MIC90=58ug.mL-1
MIC90>100ug.mL-1