HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL3406313

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2015
Volume: 25
Issue: 7
First Page: 1525
Last Page: 1531
DOI: 10.1016/j.bmcl.2015.02.018

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL943164

Protocol: N/A

Comment: Journal: J. Nat. Prod.
Year: 2007
Volume: 70
Issue: 12
First Page: 1854
Last Page: 1858
DOI: 10.1021/np070270w

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
1080	IC50	=	1080000	nM	Outside typical range
990	IC50	=	990000	nM	Outside typical range
1040	IC50	=	1040000	nM	Outside typical range
840	IC50	=	840000	nM	Outside typical range
970	IC50	=	970000	nM	Outside typical range
1040	IC50	=	1040000	nM	Outside typical range

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：NON-PROTEIN TARGET

External ID: CHEMBL3406316

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2015
Volume: 25
Issue: 7
First Page: 1525
Last Page: 1531
DOI: 10.1016/j.bmcl.2015.02.018

Target ChEMBL ID: CHEMBL3879801
ChEMBL Target Name: NON-PROTEIN TARGET
ChEMBL Target Type: NON-MOLECULAR - Target has not been defined at a molecular level, only the non-molecular entity which is affected (e.g., organism, cell line etc)
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL3406317

Protocol: N/A

Comment: Journal: Bioorg Med Chem Lett
Year: 2015
Volume: 25
Issue: 7
First Page: 1525
Last Page: 1531
DOI: 10.1016/j.bmcl.2015.02.018

Standard Type	Standard Relation	Standard Value
RatioGI50	>	20
RatioGI50	>	20
RatioGI50	>	20
RatioGI50	>	20
RatioGI50	=	0.0067
RatioGI50	>	20

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：DU-145

External ID: CHEMBL3406314

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2015
Volume: 25
Issue: 7
First Page: 1525
Last Page: 1531
DOI: 10.1016/j.bmcl.2015.02.018

Target ChEMBL ID: CHEMBL613508
ChEMBL Target Name: DU-145
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：KB

External ID: CHEMBL3406315

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem Lett
Year: 2015
Volume: 25
Issue: 7
First Page: 1525
Last Page: 1531
DOI: 10.1016/j.bmcl.2015.02.018

Target ChEMBL ID: CHEMBL398
ChEMBL Target Name: KB
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM
20	GI50	>	20000	nM

3175-95-9 靶点实验数据