Comment:
Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.
Journal: J. Med. Chem. Year: 2000 Volume: 43 Issue: 22 First Page: 4045 Last Page: 4050 DOI: 10.1021/jm000249r
Target ChEMBL ID: CHEMBL4980 ChEMBL Target Name: Neuronal acetylcholine receptor protein alpha-7 subunit ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain Relationship Type: H - Homologous protein target assigned Confidence: Homologous single protein target assigned
PubChem Standard Value
Standard Type
Standard Relation
Standard Value
Standard Units
4
Ki
=
4000
nM
3.7
Ki
=
3700
nM
0.69
Ki
=
690
nM
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader -
7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
Comment:
Journal: J. Med. Chem. Year: 2000 Volume: 43 Issue: 22 First Page: 4045 Last Page: 4050 DOI: 10.1021/jm000249r
Target ChEMBL ID: CHEMBL1907596 ChEMBL Target Name: Neuronal acetylcholine receptor; alpha4/beta2 ChEMBL Target Type: PROTEIN COMPLEX - Target is a defined protein complex, consisting of multiple subunits Relationship Type: H - Homologous protein target assigned Confidence: Homologous protein complex subunits assigned