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2989-17-5 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:3-hydroxy-3-methylglutaryl-coenzyme A reductase
External ID: CHEMBL1167858
Protocol: N/A
Comment: Journal: Bioorg. Med. Chem.
Year: 2010
Volume: 18
Issue: 12
First Page: 4238
Last Page: 4248
DOI: 10.1016/j.bmc.2010.04.096

Target ChEMBL ID: CHEMBL1163121
ChEMBL Target Name: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity CommentData Validity Comment
128.8IC50=128800nMOutside typical range
78.8IC50=78800nM
73.6IC50=73600nM
135IC50=135000nMOutside typical range
91.3IC50=91300nM
181.8IC50=181800nMOutside typical range
IC50Not Active
197.1IC50=197100nMOutside typical range