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2944-52-7 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Gamma-aminobutyric acid receptor subunit alpha-3
External ID: CHEMBL682716
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J. Med. Chem.
Year: 1998
Volume: 41
Issue: 11
First Page: 1846
Last Page: 1854
DOI: 10.1021/jm970681h

Target ChEMBL ID: CHEMBL1907607
ChEMBL Target Name: GABA-A receptor; anion channel
ChEMBL Target Type: PROTEIN COMPLEX GROUP - Target is a poorly defined protein complex, where subunit composition is unclear (e.g., GABA-A receptor)
Relationship Type: D - Direct protein target assigned
Confidence: Multiple direct protein targets may be assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
15.6IC50=15600nM
9.4IC50=9400nM
739IC50=739000nMOutside typical range
6.52IC50=6520nM
23.6IC50=23600nM
1.44IC50=1440nM
1.95IC50=1950nM
39.5IC50=39500nM
1.07IC50=1070nM
37IC50=37000nM
131IC50=131000nMOutside typical range
15.2IC50=15200nM
8.5IC50=8500nM
0.3IC50=300nM