HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5160988

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160991

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	NA
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160985

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	NA
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5160984

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160987

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Stability	=	19	%
Stability	=	33	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5160986

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160983

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160982

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	Non-Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161029

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value
BPR	=	0.205

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161028

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
Ct	=	15.7	ng/g

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：fMet-Leu-Phe receptor

External ID: CHEMBL5161031

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL3359
ChEMBL Target Name: Formyl peptide receptor 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Efficacy	=	120	%
Efficacy	=	80	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N-formyl peptide receptor 2

External ID: CHEMBL5161030

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4227
ChEMBL Target Name: Lipoxin A4 receptor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Efficacy	=	110	%
Efficacy	=	100	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161025

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
Tlast	=	8	hr

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161024

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
AUC	=	731	ng.hr.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161027

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value
BPR	=	0.378

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161026

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
Ct	=	37	ng/g

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161021

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
Clast	=	14.1	ng/ml

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161022

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
AUC	=	613	ng.hr.mL-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161017

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	1053	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161016

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	264	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161019

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	89	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161018

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	100	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161013

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	1131	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161012

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	182	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161015

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	112	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161014

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	105	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161009

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	121	%
Activity	=	95	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161008

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	103	%
Activity	=	102	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161011

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	103	%
Activity	=	122	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161010

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	108	%
Activity	=	97	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161005

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161004

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161007

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161006

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161001

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5161000

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	NA
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161003

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Microglia

External ID: CHEMBL5161002

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Target ChEMBL ID: CHEMBL4296521
ChEMBL Target Name: Microglia
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160997

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160996

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
CL	=	29	mL.min-1.g-1
CL	=	15.8	mL.min-1.g-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160999

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	NA
Activity	NA

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160998

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5160995

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2022
Volume: 65
Issue: 6.0
First Page: 5004
Last Page: 5028
DOI: 10.1021/acs.jmedchem.1c02203

Standard Type	Standard Relation	Standard Value	Standard Units
T1/2	=	0.4	hr
T1/2	=	0.7333	hr

2829263-19-4 靶点实验数据