HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Endolysin

External ID: CHEMBL2330736

Protocol: N/A

Comment: Journal: J Med Chem
Year: 2013
Volume: 56
Issue: 7
First Page: 2874
Last Page: 2884
DOI: 10.1021/jm301823g

Target ChEMBL ID: CHEMBL5206
ChEMBL Target Name: Lysozyme
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
Delta Tm	=	-0.3	degrees C
Delta Tm	=	5	degrees C
Delta Tm	=	2.1	degrees C
Delta Tm	=	1.2	degrees C
Delta Tm	=	0.2	degrees C
Delta Tm	=	0.5	degrees C
Delta Tm	=	0.4	degrees C
Delta Tm	=	-0.3	degrees C
Delta Tm	=	-0.7	degrees C
Delta Tm	=	1.9	degrees C
Delta Tm	=	-0.1	degrees C
Delta Tm	=	0.1	degrees C
Delta Tm	=	0.3	degrees C
Delta Tm	=	1.1	degrees C
Delta Tm	=	2.2	degrees C
Delta Tm	=	-0.6	degrees C
Delta Tm	=	0.2	degrees C
Delta Tm	=	0.2	degrees C
Delta Tm	=	-0.3	degrees C
Delta Tm	=	0.4	degrees C

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL629624

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 19
First Page: 2497
Last Page: 2502
DOI: 10.1016/S0960-894X(97)10003-8

Standard Type	Standard Relation	Standard Value	Standard Units
k cat/Km	=	0.6	M-1 s-1
k cat/Km	=	39	M-1 s-1
k cat/Km	=	6	M-1 s-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL850875

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 19
First Page: 2497
Last Page: 2502
DOI: 10.1016/S0960-894X(97)10003-8

Standard Type	Standard Relation	Standard Value
Ratio	=	32
Ratio	=	48
Ratio	=	38

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL857732

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem. Lett.
Year: 1997
Volume: 7
Issue: 19
First Page: 2497
Last Page: 2502
DOI: 10.1016/S0960-894X(97)10003-8

Standard Type	Standard Relation	Standard Value	Standard Units
K amine	=	0.0185	M-1 s-1
K amine	=	0.82	M-1 s-1
K amine	=	0.16	M-1 s-1

271-95-4 靶点实验数据