HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380365

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380366

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Active
Drug uptake	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380367

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Active
Drug uptake	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380368

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Active
Drug uptake	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380369

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Active
Drug uptake	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380370

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380371

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
2.66	TC50	=	2.66	uM
1.04	TC50	=	1.04	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380372

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.5	IC50	=	500	nM
0.1	IC50	=	100	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL4380357

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	13.1	mg
Activity	=	12.9	mg
Activity	=	13.3	mg

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380358

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Standard Relation	Standard Value
LogP	=	3.77
LogP	=	2.36
LogP	=	1.59

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380359

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380360

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380362

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity				Active
Activity	=	660	nm
Activity	=	660	nm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380363

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	661	nm
Activity	=	661	nm
Activity	=	661	nm

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380364

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Standard Relation	Standard Value	Standard Units
K	=	0.0081	/s
K	=	0.0313	/s
K	=	0.027	/s

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380352

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
TI	=	8.74
TI	=	8.97

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL4380353

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-Toxic
Activity	Non-Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL4380354

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	13.3	mg
Activity	=	12.9	mg
Activity	=	13.4	mg

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL4380355

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	13.2	mg
Activity	=	13.5	mg
Activity	=	12.9	mg

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL4380356

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	12.7	mg
Activity	=	13.1	mg
Activity	=	13.2	mg

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL4380397

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	59.2	mg
Activity	=	43.6	mg
Activity	=	41.9	mg

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL4380398

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	100.3	mg
Activity	=	75.2	mg
Activity	=	74.3	mg

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL4380399

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-Toxic
Activity	Non-Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL4380400

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-Toxic
Activity	Non-Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380401

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Standard Relation	Standard Value
Ratio	=	0.405
Ratio	=	1.565
Ratio	=	1.35

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380402

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380403

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380404

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Active
Drug uptake	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380389

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Not Active
Drug uptake	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380390

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Not Active
Drug uptake	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380391

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Not Active
Drug uptake	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380392

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Not Active
Drug uptake	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380393

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Active
Drug uptake	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL4380394

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-Toxic
Activity	Non-Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL4380395

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Cavia porcellus

External ID: CHEMBL4380396

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL369
ChEMBL Target Name: Cavia porcellus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	57.2	mg
Activity	=	42.3	mg
Activity	=	41.6	mg

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380381

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	2.3	%
Activity	=	2.75	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380382

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380383

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	0.0138	g
Activity	=	0.0296	g

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380384

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380385

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380386

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380387

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Active
Drug uptake	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL4380388

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Standard Type	Activity Comment
Drug uptake	Not Active
Drug uptake	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380373

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	30.69	%
Activity	=	34.15	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380374

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	3.13	%
Activity	=	2.64	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380375

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	2.07	%
Activity	=	28.92	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380376

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	83.88	%
Activity	=	67.73	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380377

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	10.92	%
Activity	=	0.7	%

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：A549

External ID: CHEMBL4380378

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2020
Volume: 187
First Page: 111959
Last Page: 111959
DOI: 10.1016/j.ejmech.2019.111959

Target ChEMBL ID: CHEMBL392
ChEMBL Target Name: A549
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units
Activity	=	89.84	%
Activity	=	87.84	%

2344751-92-2 靶点实验数据