HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Nitric oxide synthase, brain

External ID: CHEMBL1002712

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2008
Volume: 16
Issue: 11
First Page: 6193
Last Page: 6206
DOI: 10.1016/j.bmc.2008.04.036

Target ChEMBL ID: CHEMBL3568
ChEMBL Target Name: Nitric-oxide synthase, brain
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
0.13	Ki	=	130	nM
0.68	Ki	=	680	nM
0.0087	Ki	=	8.7	nM
0.04	Ki	=	40	nM
0.04	Ki	=	40	nM
0.41	Ki	=	410	nM
3.3	Ki	=	3300	nM
0.5	Ki	=	500	nM
0.1	Ki	=	100	nM	Potential transcription error
3	Ki	=	3000	nM
5.3	Ki	=	5300	nM
0.36	Ki	=	360	nM
0.89	Ki	=	890	nM
125	Ki	=	125000	nM	Outside typical range
32	Ki	=	32000	nM
35	Ki	=	35000	nM
2	Ki	=	2000	nM
65	Ki	=	65000	nM
2	Ki	=	2000	nM
125	Ki	=	125000	nM	Outside typical range

22906-75-8 靶点实验数据