HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：MRC5

External ID: CHEMBL2095143

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL614181
ChEMBL Target Name: MRC5
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: Drugs for Neglected Diseases Initiative (DNDi)

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
41.67	IC50	>	41670	nM
20.83	IC50	>	20830	nM
41.67	IC50	>	41670	nM
2.25	IC50	=	2250	nM
20.83	IC50	>	20830	nM
2.08	IC50	>	2080	nM
4.17	IC50	>	4170	nM
41.67	IC50	>	41670	nM
41.67	IC50	>	41670	nM
20.83	IC50	>	20830	nM
20.83	IC50	>	20830	nM
20.83	IC50	>	20830	nM
4.17	IC50	>	4170	nM
20.83	IC50	>	20830	nM
5.76	IC50	=	5760	nM
10.42	IC50	>	10420	nM
41.67	IC50	>	41670	nM
41.67	IC50	>	41670	nM
4.95	IC50	=	4950	nM
4.17	IC50	>	4170	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Trypanosoma brucei brucei

External ID: CHEMBL2095144

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Target ChEMBL ID: CHEMBL612851
ChEMBL Target Name: Trypanosoma brucei brucei
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Data Source: Drugs for Neglected Diseases Initiative (DNDi)

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
4.57	IC50	=	4570	nM
2.62	IC50	=	2620	nM
1.95	IC50	=	1950	nM
0.245	IC50	=	245	nM
2.44	IC50	=	2440	nM
5.08	IC50	=	5080	nM
0.524	IC50	=	524	nM
0.049	IC50	=	49	nM
0.004	IC50	<	4	nM
3.82	IC50	=	3820	nM
7.34	IC50	=	7340	nM
12.56	IC50	=	12560	nM
5.11	IC50	=	5110	nM
0.557	IC50	=	557	nM
5.72	IC50	=	5720	nM
5.24	IC50	=	5240	nM
5.48	IC50	=	5480	nM
2.58	IC50	=	2580	nM
3.73	IC50	=	3730	nM
2.43	IC50	=	2430	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycoplasmoides gallisepticum

External ID: CHEMBL712219

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 1991
Volume: 34
Issue: 3
First Page: 1193
Last Page: 1201
DOI: 10.1021/jm00107a045

Target ChEMBL ID: CHEMBL612643
ChEMBL Target Name: Mycoplasmoides gallisepticum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	MIC	>	100000	nM
0.1	MIC	=	100	nM
100	MIC	>	100000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mycoplasmoides gallisepticum

External ID: CHEMBL712220

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: J Med Chem
Year: 1991
Volume: 34
Issue: 3
First Page: 1193
Last Page: 1201
DOI: 10.1021/jm00107a045

Target ChEMBL ID: CHEMBL612643
ChEMBL Target Name: Mycoplasmoides gallisepticum
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
0.046	MIC	=	46	nM
0.1	MIC	=	100	nM
0.2	MIC	=	200	nM

22426-18-2 靶点实验数据