HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Hippocampus

External ID: CHEMBL2090620

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 57
First Page: 268
Last Page: 274
DOI: 10.1016/j.ejmech.2012.09.007

Target ChEMBL ID: CHEMBL613631
ChEMBL Target Name: Hippocampus
ChEMBL Target Type: TISSUE - Target is a healthy or diseased tissue
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Non-toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：C6

External ID: CHEMBL2090218

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 57
First Page: 268
Last Page: 274
DOI: 10.1016/j.ejmech.2012.09.007

Target ChEMBL ID: CHEMBL614657
ChEMBL Target Name: C6
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：C6

External ID: CHEMBL2090221

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 57
First Page: 268
Last Page: 274
DOI: 10.1016/j.ejmech.2012.09.007

Target ChEMBL ID: CHEMBL614657
ChEMBL Target Name: C6
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：C6

External ID: CHEMBL2090219

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2012
Volume: 57
First Page: 268
Last Page: 274
DOI: 10.1016/j.ejmech.2012.09.007

Target ChEMBL ID: CHEMBL614657
ChEMBL Target Name: C6
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：U-937

External ID: CHEMBL1074620

Protocol: N/A

Comment: Journal: Bioorg. Med. Chem.
Year: 2009
Volume: 17
Issue: 18
First Page: 6547
Last Page: 6559
DOI: 10.1016/j.bmc.2009.08.002

Target ChEMBL ID: CHEMBL612794
ChEMBL Target Name: U-937
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
704	CC50	=	704000	nM
790	CC50	=	790000	nM
2000	CC50	>	2000000	nM
2000	CC50	>	2000000	nM
535	CC50	=	535000	nM
252	CC50	=	252000	nM
2000	CC50	>	2000000	nM
2000	CC50	>	2000000	nM
2000	CC50	>	2000000	nM
266	CC50	=	266000	nM
420	CC50	=	420000	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：U-937

External ID: CHEMBL1065376

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem.
Year: 2009
Volume: 17
Issue: 18
First Page: 6547
Last Page: 6559
DOI: 10.1016/j.bmc.2009.08.002

Target ChEMBL ID: CHEMBL612794
ChEMBL Target Name: U-937
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Data Validity Comment
400	IC50	>	400000	nM	Outside typical range
182.1	IC50	=	182100	nM	Outside typical range
400	IC50	>	400000	nM	Outside typical range
400	IC50	>	400000	nM	Outside typical range
177.3	IC50	=	177300	nM	Outside typical range
2.2	IC50	=	2200	nM
400	IC50	>	400000	nM	Outside typical range
255.4	IC50	=	255400	nM	Outside typical range
400	IC50	>	400000	nM	Outside typical range
3.5	IC50	=	3500	nM
191.9	IC50	=	191900	nM	Outside typical range

22357-13-7 靶点实验数据