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2148317-51-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Bile acid receptor
External ID: CHEMBL5336740
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2023
Volume: 261
First Page: 115851
Last Page: 115851
DOI: 10.1016/j.ejmech.2023.115851

Target ChEMBL ID: CHEMBL2047
ChEMBL Target Name: Bile acid receptor FXR
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Efficacy=26%
Efficacy=13%
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:G-protein coupled bile acid receptor 1
External ID: CHEMBL5336738
Protocol: N/A
Comment: Journal: Eur J Med Chem
Year: 2023
Volume: 261
First Page: 115851
Last Page: 115851
DOI: 10.1016/j.ejmech.2023.115851

Target ChEMBL ID: CHEMBL5409
ChEMBL Target Name: G-protein coupled bile acid receptor 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Efficacy=35%
Efficacy=120.5%
Efficacy=100%