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2140-77-4 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Eukaryotic translation initiation factor 4E
External ID: CHEMBL831921
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2005
Volume: 15
Issue: 8
First Page: 2177
Last Page: 2180
DOI: 10.1016/j.bmcl.2005.01.080

Target ChEMBL ID: CHEMBL4848
ChEMBL Target Name: Eukaryotic translation initation factor
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsData Validity Comment
85IC50=85000nM
400IC50>400000nMOutside typical range
220IC50=220000nMOutside typical range