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21124-40-3 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Voltage-dependent calcium channel subunit alpha-2/delta-1
External ID: CHEMBL859414
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg. Med. Chem. Lett.
Year: 2006
Volume: 16
Issue: 5
First Page: 1138
Last Page: 1141
DOI: 10.1016/j.bmcl.2005.11.108

Target ChEMBL ID: CHEMBL4676
ChEMBL Target Name: Voltage-gated calcium channel alpha2/delta subunit 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard Units
0.12023Ki=120.23nM
1.86209Ki=1862.09nM
20Ki=20000nM
0.06Ki=60nM
0.06026Ki=60.26nM
0.18Ki=180nM
0.18197Ki=181.97nM
30Ki=30000nM
30.1995Ki=30199.52nM
0.09Ki=90nM
0.08913Ki=89.13nM
100Ki>100000nM
5.4Ki=5400nM
5.37032Ki=5370.32nM
0.031Ki=31nM
0.0309Ki=30.9nM
0.12Ki=120nM
0.10965Ki=109.65nM
0.1Ki=100nM
0.10471Ki=104.71nM