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2035-93-0 靶点实验数据

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Transient receptor potential cation channel subfamily A member 1
External ID: CHEMBL5577374
Protocol: N/A
Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Bioorg Med Chem
Year: 2024
Volume: 110
First Page: 117812
Last Page: 117812
DOI: 10.1016/j.bmc.2024.117812

Target ChEMBL ID: CHEMBL6007
ChEMBL Target Name: Transient receptor potential cation channel subfamily A member 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
PubChem Standard ValueStandard TypeStandard RelationStandard ValueStandard UnitsActivity Comment
1.13IC50=1130nM
ActivityNot Active
IC50Not Determined
IC50Not Determined
ActivityNot Active
4.25IC50=4250nM
ActivityNot Active
8.35IC50=8350nM
ActivityNot Active
ActivityNot Active
ActivityNot Active
13.94IC50=13940nM
ActivityNot Active
HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16
来源:ChEMBL 靶标:Transient receptor potential cation channel subfamily A member 1
External ID: CHEMBL5577375
Protocol: N/A
Comment: Journal: Bioorg Med Chem
Year: 2024
Volume: 110
First Page: 117812
Last Page: 117812
DOI: 10.1016/j.bmc.2024.117812

Target ChEMBL ID: CHEMBL6007
ChEMBL Target Name: Transient receptor potential cation channel subfamily A member 1
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned
Standard TypeStandard RelationStandard ValueStandard Units
Activity=27%
Activity=39%
Activity=136%
Activity=80%
Activity=103%
Activity=91%
Activity=115%
Activity=116%
Activity=80%
Activity=0.5%
Activity=102%
Activity=111%
Activity=100%