HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL1212145

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2010
Volume: 45
Issue: 8
First Page: 3299
Last Page: 3310
DOI: 10.1016/j.ejmech.2010.04.013

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
	EC50				Not Determined
60	EC50	>	60000	nM
	EC50				Not Determined
60	EC50	>	60000	nM
2.7	EC50	=	2700	nM
	EC50				Not Determined
60	EC50	>	60000	nM
60	EC50	>	60000	nM
60	EC50	>	60000	nM
60	EC50	>	60000	nM
6.8	EC50	=	6800	nM
60	EC50	>	60000	nM
8.8	EC50	=	8800	nM
60	EC50	>	60000	nM
60	EC50	>	60000	nM
60	EC50	>	60000	nM
	EC50				Not Determined
3.9	EC50	=	3900	nM
60	EC50	>	60000	nM
	EC50				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HaCaT

External ID: CHEMBL1212144

Protocol: N/A

Comment: Journal: Eur. J. Med. Chem.
Year: 2010
Volume: 45
Issue: 8
First Page: 3299
Last Page: 3310
DOI: 10.1016/j.ejmech.2010.04.013

Target ChEMBL ID: CHEMBL614392
ChEMBL Target Name: HaCaT
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value	Standard Units	Activity Comment
Activity	=	122.8	mU/ml
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity	=	61.2	mU/ml
Activity				Not Determined
Activity				Not Determined
Activity				Not Determined
Activity	=	69.9	mU/ml
Activity				Not Determined
Activity				Not Determined

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：HaCaT

External ID: CHEMBL1212143

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur. J. Med. Chem.
Year: 2010
Volume: 45
Issue: 8
First Page: 3299
Last Page: 3310
DOI: 10.1016/j.ejmech.2010.04.013

Target ChEMBL ID: CHEMBL614392
ChEMBL Target Name: HaCaT
ChEMBL Target Type: CELL-LINE - Target is a specific cell-line
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
34.3	IC50	=	34300	nM
50	IC50	>	50000	nM
50	IC50	>	50000	nM
46.3	IC50	=	46300	nM
19.8	IC50	=	19800	nM
8.8	IC50	=	8800	nM
5.2	IC50	=	5200	nM
10.8	IC50	=	10800	nM
50	IC50	>	50000	nM
50	IC50	>	50000	nM
10	IC50	=	10000	nM
50	IC50	>	50000	nM
17.5	IC50	=	17500	nM
4.5	IC50	=	4500	nM
50	IC50	>	50000	nM
48.8	IC50	=	48800	nM
2	IC50	=	2000	nM
28.3	IC50	=	28300	nM
25.7	IC50	=	25700	nM
50	IC50	>	50000	nM

20168-55-2 靶点实验数据