HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5249376

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Standard Type	Activity Comment
Activity	Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL5249375

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Standard Type	Activity Comment
Activity	Toxic
Activity	Non-Toxic

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL5249372

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL5249371

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL5249374

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Activity_index	=	0.291
Activity_index	=	0.138

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL5249373

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Activity_index	=	0.009
Activity_index	=	0.038

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL5249368

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Active
Activity	Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL5249367

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Activity Comment
Activity	Not Active

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL5249370

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Activity_index	=	0.075
Activity_index	=	0.111

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Mus musculus

External ID: CHEMBL5249369

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL375
ChEMBL Target Name: Mus musculus
ChEMBL Target Type: ORGANISM - Target is a complete organism
Relationship Type: N - Non-molecular target assigned
Confidence: Target assigned is non-molecular

Standard Type	Standard Relation	Standard Value
Activity_index	=	0.375
Activity_index	=	0.185

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 14

External ID: CHEMBL5249364

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL3510
ChEMBL Target Name: Carbonic anhydrase XIV
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
3.2	Ka	=	3.2	uM
9.5	Ka	=	9.5	uM
2.6	Ka	=	2.6	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 13

External ID: CHEMBL5249363

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL3912
ChEMBL Target Name: Carbonic anhydrase XIII
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
49.7	Ka	=	49.7	uM
38.2	Ka	=	38.2	uM
46.9	Ka	=	46.9	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B

External ID: CHEMBL5249366

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL2039
ChEMBL Target Name: Monoamine oxidase B
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
13.4	IC50	=	13400	nM
64.8	IC50	=	64800	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Amine oxidase [flavin-containing] A

External ID: CHEMBL5249365

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL1951
ChEMBL Target Name: Monoamine oxidase A
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
25.4	IC50	=	25400	nM
14	IC50	=	14000	nM
10.5	IC50	=	10500	nM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 7

External ID: CHEMBL5249360

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL2326
ChEMBL Target Name: Carbonic anhydrase VII
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
41.2	Ka	=	41.2	uM
44.9	Ka	=	44.9	uM
13.4	Ka	=	13.4	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 6

External ID: CHEMBL5249359

Protocol: N/A

Comment: Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL3025
ChEMBL Target Name: Carbonic anhydrase VI
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
73.1	Ka	=	73.1	uM
37.8	Ka	=	37.8	uM
48.5	Ka	=	48.5	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 12

External ID: CHEMBL5249362

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL3242
ChEMBL Target Name: Carbonic anhydrase XII
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
52.5	Ka	=	52.5	uM
52.8	Ka	=	52.8	uM
90.6	Ka	=	90.6	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 9

External ID: CHEMBL5249361

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL3594
ChEMBL Target Name: Carbonic anhydrase IX
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
22.2	Ka	=	22.2	uM
47.9	Ka	=	47.9	uM
22.8	Ka	=	22.8	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 4

External ID: CHEMBL5249356

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL3729
ChEMBL Target Name: Carbonic anhydrase IV
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
5.9	Ka	=	5.9	uM
8.2	Ka	=	8.2	uM
6.1	Ka	=	6.1	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 3

External ID: CHEMBL5249355

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL2885
ChEMBL Target Name: Carbonic anhydrase III
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
59.7	Ka	=	59.7	uM
77.3	Ka	=	77.3	uM
13.1	Ka	=	13.1	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 5B, mitochondrial

External ID: CHEMBL5249358

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL3969
ChEMBL Target Name: Carbonic anhydrase VB
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
21.7	Ka	=	21.7	uM
22.5	Ka	=	22.5	uM
20.2	Ka	=	20.2	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 5A, mitochondrial

External ID: CHEMBL5249357

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL4789
ChEMBL Target Name: Carbonic anhydrase VA
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
14.2	Ka	=	14.2	uM
3.3	Ka	=	3.3	uM
13.1	Ka	=	13.1	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 2

External ID: CHEMBL5249354

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL205
ChEMBL Target Name: Carbonic anhydrase II
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
100	Ka	>	100	uM
100	Ka	>	100	uM
100	Ka	>	100	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Carbonic anhydrase 1

External ID: CHEMBL5249353

Protocol: N/A

Comment: Compounds with activity <= 10uM or explicitly reported as active by ChEMBL are flagged as active in this PubChem assay presentation.

Journal: Eur J Med Chem
Year: 2022
Volume: 244
First Page: 114828
Last Page: 114828
DOI: 10.1016/j.ejmech.2022.114828

Target ChEMBL ID: CHEMBL261
ChEMBL Target Name: Carbonic anhydrase I
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: D - Direct protein target assigned
Confidence: Direct single protein target assigned

PubChem Standard Value	Standard Type	Standard Relation	Standard Value	Standard Units
9.9	Ka	=	9.9	uM
4.6	Ka	=	4.6	uM
19.6	Ka	=	19.6	uM

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B

External ID: CHEMBL731135

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 10
First Page: 1354
Last Page: 1357
DOI: 10.1021/jm00376a024

Target ChEMBL ID: CHEMBL2111399
ChEMBL Target Name: Monoamine oxidase
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Activity Comment
k cat	No activity
k cat	No activity

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B

External ID: CHEMBL731139

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 10
First Page: 1354
Last Page: 1357
DOI: 10.1021/jm00376a024

Target ChEMBL ID: CHEMBL2111399
ChEMBL Target Name: Monoamine oxidase
ChEMBL Target Type: PROTEIN FAMILY - Target is a group of closely related proteins
Relationship Type: H - Homologous protein target assigned
Confidence: Multiple homologous protein targets may be assigned

Standard Type	Standard Units	Activity Comment
Km	nM	No activity
Km	nM	No activity

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL844613

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 10
First Page: 1354
Last Page: 1357
DOI: 10.1021/jm00376a024

Standard Type	Activity Comment
Ratio	No activity
Ratio	No activity

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：N/A

External ID: CHEMBL844611

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 10
First Page: 1354
Last Page: 1357
DOI: 10.1021/jm00376a024

Standard Type	Standard Relation	Standard Value	Standard Units
Ratio	=	42000	M-1 s-1
Ratio	=	590	M-1 s-1
Ratio	=	9300	M-1 s-1
Ratio	=	8300	M-1 s-1
Ratio	=	6700	M-1 s-1
Ratio	=	1000	M-1 s-1
Ratio	=	2300	M-1 s-1

HepG2 Cytotoxicity Assay Measured in Cell-Based System Using Plate Reader - 7071-02_Inhibitor_Dose_DryPowder_Activity_Set16

来源：ChEMBL 靶标：Dopamine beta-hydroxylase

External ID: CHEMBL667713

Protocol: N/A

Comment: Journal: J. Med. Chem.
Year: 1984
Volume: 27
Issue: 10
First Page: 1354
Last Page: 1357
DOI: 10.1021/jm00376a024

Target ChEMBL ID: CHEMBL4702
ChEMBL Target Name: Dopamine beta-hydroxylase
ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain
Relationship Type: H - Homologous protein target assigned
Confidence: Homologous single protein target assigned

Standard Type	Standard Relation	Standard Value	Standard Units
k cat	=	85	s-1
k cat	=	12	s-1
k cat	=	65	s-1
k cat	=	36	s-1
k cat	=	44	s-1
k cat	=	20	s-1
k cat	=	39	s-1

2014-77-9 靶点实验数据